Three-dimensional reconstruction displaying typical cortical thickness in HI rats as compared with LI rats suggests that the higher the impulsivity the thinner the insula. A correlational analysis between the thickness result from significant voxels in the insula cortex and impulsivity (premature responding rate (%) in the 5-choice serial reaction time task) revealed that those rats having higher rates of premature responding exhibit thinner insular cortices (R2=0.62, P<0.0001).
Impulsivity is predicted by the thinness of the insular cortex in rats / Belin Rauscent, A.; Daniel, M. L.; Puaud, M.; Jupp, B.; Sawiak, S.; Howett, D.; Mckenzie, C.; Caprioli, Daniele; Besson, M.; Robbins, T. W.; Everitt, B. J.; Dalley, J. W.; Belin, D.. - In: MOLECULAR PSYCHIATRY. - ISSN 1359-4184. - 21:4(2016), pp. 445-445. [10.1038/mp.2016.32]
Impulsivity is predicted by the thinness of the insular cortex in rats
CAPRIOLI, DANIELEMembro del Collaboration Group
;
2016
Abstract
Three-dimensional reconstruction displaying typical cortical thickness in HI rats as compared with LI rats suggests that the higher the impulsivity the thinner the insula. A correlational analysis between the thickness result from significant voxels in the insula cortex and impulsivity (premature responding rate (%) in the 5-choice serial reaction time task) revealed that those rats having higher rates of premature responding exhibit thinner insular cortices (R2=0.62, P<0.0001).| File | Dimensione | Formato | |
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