Anastomotic leak following colorectal surgery can be a devastating adverse event. The ideal stapling device should be capable of rapid creation of an anastomosis with serosal apposition without the persistence of a foreign body or a foreign body reaction which potentially contribute to early anastomotic dehiscence or late anastomotic stricture. A systematic review was performed examining available data on controlled randomized and non-randomized trials assessing the NiTi compression anastomosis ring-(NiTi CAR™) (NiTi Solutions, Netanyah Israel) in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) standards. A protocol for this meta-analysis has been registered on PROSPERO (CRD42016050934). The initial search yielded 45 potentially relevant articles. After screening titles and abstracts for relevance and assessment for eligibility, 39 of these articles were eventually excluded leaving 6 studies for analysis in the review. Regarding the primary outcome measure, the overall anastomotic leak rate was 2.2% (5/230) in the compression anastomosis group compared with 3% (10/335) in the conventional anastomosis group; this difference was not statistically significant (RR 0.75, 95% CI 0.25-2.24; participants = 565; studies = 6; I 2 = 0%). There were no statistically significant differences between compression and conventional anastomoses in any of the secondary outcomes. This review was unable to demonstrate any statistically significant differences in favor of the compression anastomosis technique over conventional manual or stapled mechanical anastomoses.

A systematic analysis of controlled clinical trials using the NiTi CAR™ compression ring in colorectal anastomoses / Tabola, R.; Cirocchi, R.; Fingerhut, A.; Arezzo, A.; Randolph, J.; Grassi, V.; Binda, G. A.; D'Andrea, Vito; Abraha, I.; Popivanov, G.; Di Saverio, S.; Zbar, A.. - In: TECHNIQUES IN COLOPROCTOLOGY. - ISSN 1123-6337. - STAMPA. - 21:3(2017), pp. 177-184. [10.1007/s10151-017-1583-2]

A systematic analysis of controlled clinical trials using the NiTi CAR™ compression ring in colorectal anastomoses

D'ANDREA, Vito;
2017

Abstract

Anastomotic leak following colorectal surgery can be a devastating adverse event. The ideal stapling device should be capable of rapid creation of an anastomosis with serosal apposition without the persistence of a foreign body or a foreign body reaction which potentially contribute to early anastomotic dehiscence or late anastomotic stricture. A systematic review was performed examining available data on controlled randomized and non-randomized trials assessing the NiTi compression anastomosis ring-(NiTi CAR™) (NiTi Solutions, Netanyah Israel) in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) standards. A protocol for this meta-analysis has been registered on PROSPERO (CRD42016050934). The initial search yielded 45 potentially relevant articles. After screening titles and abstracts for relevance and assessment for eligibility, 39 of these articles were eventually excluded leaving 6 studies for analysis in the review. Regarding the primary outcome measure, the overall anastomotic leak rate was 2.2% (5/230) in the compression anastomosis group compared with 3% (10/335) in the conventional anastomosis group; this difference was not statistically significant (RR 0.75, 95% CI 0.25-2.24; participants = 565; studies = 6; I 2 = 0%). There were no statistically significant differences between compression and conventional anastomoses in any of the secondary outcomes. This review was unable to demonstrate any statistically significant differences in favor of the compression anastomosis technique over conventional manual or stapled mechanical anastomoses.
2017
Compression anastomosis - NiTi CAR - ColonRing - Biofragmentable anastomotic ring - BAR - Anastomotic leak
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
A systematic analysis of controlled clinical trials using the NiTi CAR™ compression ring in colorectal anastomoses / Tabola, R.; Cirocchi, R.; Fingerhut, A.; Arezzo, A.; Randolph, J.; Grassi, V.; Binda, G. A.; D'Andrea, Vito; Abraha, I.; Popivanov, G.; Di Saverio, S.; Zbar, A.. - In: TECHNIQUES IN COLOPROCTOLOGY. - ISSN 1123-6337. - STAMPA. - 21:3(2017), pp. 177-184. [10.1007/s10151-017-1583-2]
File allegati a questo prodotto
File Dimensione Formato  
Tabola_NiTi-CAR_2017.pdf

solo utenti autorizzati

Note: Articolo principale
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 865.59 kB
Formato Adobe PDF
865.59 kB Adobe PDF   Contatta l'autore

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/926618
Citazioni
  • ???jsp.display-item.citation.pmc??? 3
  • Scopus 6
  • ???jsp.display-item.citation.isi??? 6
social impact