Chromatin structure seems related to the DNA linker length. This paper presents a systematic search of the possible chromatin structure as a function of the linker lengths, starting from three different low-resolution molecular models of the nucleosome. Gay-Berne potential was used to evaluate the relative nucleosome packing energy. Results suggest that linker DNAs, which bridges and orientate nucleosomes, affect both the geometry and the rigidity of the global chromatin structure. (c) 2004 Elsevier B.V. All rights reserved.
Theoretical models of possible compact nucleosome structures / Neva, Besker; Anselmi, Claudio; DE SANTIS, Pasquale. - In: BIOPHYSICAL CHEMISTRY. - ISSN 0301-4622. - STAMPA. - 115:2-3 SPEC. ISS.(2005), pp. 139-143. (Intervento presentato al convegno International Symposium on Biology after the Genome - A Physical View tenutosi a Zaragoza, SPAIN nel FEB 11-13, 2004) [10.1016/j.bpc.2004.12.044].
Theoretical models of possible compact nucleosome structures
ANSELMI, Claudio;DE SANTIS, Pasquale
2005
Abstract
Chromatin structure seems related to the DNA linker length. This paper presents a systematic search of the possible chromatin structure as a function of the linker lengths, starting from three different low-resolution molecular models of the nucleosome. Gay-Berne potential was used to evaluate the relative nucleosome packing energy. Results suggest that linker DNAs, which bridges and orientate nucleosomes, affect both the geometry and the rigidity of the global chromatin structure. (c) 2004 Elsevier B.V. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
