Chiral Basket Resorc[4]arenes are well known chiral solvating agents that can induce enantiodiscrimination towards aminoacids, peptides and nucleosides. We synthesized both enantiomer of some basket resorc[4]arenes capable of forming stable diasteromeric host-guest complexes with some nucleosides like cytidine and cytarabine. The reactivity and the structures of the complexes were investigated in gas-phase (ESI-IRMPD, ESI-FT-ICR) and in solution (DOSY, ROESY). Different "in" and "out" structures were found both in solution and in gas-phase, moreover the results were supported by theoretical calculations.
Chiral Supramolecular Chemistry of Basket Resorc[4]arenes / Calcaterra, Andrea. - (2013 Feb 11).
Chiral Supramolecular Chemistry of Basket Resorc[4]arenes
CALCATERRA, ANDREA
11/02/2013
Abstract
Chiral Basket Resorc[4]arenes are well known chiral solvating agents that can induce enantiodiscrimination towards aminoacids, peptides and nucleosides. We synthesized both enantiomer of some basket resorc[4]arenes capable of forming stable diasteromeric host-guest complexes with some nucleosides like cytidine and cytarabine. The reactivity and the structures of the complexes were investigated in gas-phase (ESI-IRMPD, ESI-FT-ICR) and in solution (DOSY, ROESY). Different "in" and "out" structures were found both in solution and in gas-phase, moreover the results were supported by theoretical calculations.File | Dimensione | Formato | |
---|---|---|---|
Chiral Supramolecular Chemistry of Basket Resorc[4]arenes.pdf
accesso aperto
Note: Tesi di Dottorato
Tipologia:
Tesi di dottorato
Licenza:
Creative commons
Dimensione
2.93 MB
Formato
Adobe PDF
|
2.93 MB | Adobe PDF |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.