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Characterising young exoplanets and their host stars

A few decades ago, the first planet outside the Solar System ("exoplanet") was discovered. This marked a turning point in the field, since the number of exoplanets from that time is exponentially raising. However, many questions on planetary formation and their evolution with respect to the protoplanetary disc environment and the stellar host characteristics still remain. Many methods of analysis and data reduction techniques were developed over time, as well as technological improvements of...

The role of RNA-RNA interactions in the post-transcriptional control of cancer-related genes: the case of circHIPK3/BRCA1 mRNA pairing

Circular RNAs are covalently-closed RNA molecules involved in gene-expression regulation at different levels. These peculiar molecules have recently attracted the attention of the scientific community especially due to their deregulation in different pathological conditions and recent technologies advances have allowed to better define their role in the cell. The work I carried out during my PhD aimed at elucidating the molecular mechanism through which the circular RNA circHIPK3, which re...

Potere e classi sociali oggi. Una teoria neomarxista integrata dello sfruttamento e delle classi sociali per l’analisi della struttura e delle diseguaglianze di classe nell’Italia contemporanea in prospettiva europea (1992-2020)

Il testo presenta una ricostruzione di una teoria neomarxista integrata dello sfruttamento e delle classi sociali finalizzata all’analisi della struttura e delle diseguaglianze di classe nell’Italia contemporanea (1992-2020) in prospettiva europea. Il primo capitolo ripercorre in prospettiva storico-analitica le teorie e i modelli che vengono adoperati come fonti per la ricostruzione della teoria presentata nei capitoli successivi. A questo scopo, in una rapida ricognizione analitica, il test...

Benchtop FT-NMR: a versatile tool for customs applications and food challenges

This doctoral thesis explores the application of low-field benchtop nuclear magnetic resonance spectroscopy based on Fourier transform (Benchtop FT-NMR), used as an innovative technology for the identification and quantification of substances in customs, forensic, and food sectors. Both one- and two-dimensional spectra of various nuclei (¹H, ¹³C, ¹⁹F, ²³Na) were employed. The work is divided into two main sections: the first focuses on forensic analysis and the control of narcotic substances...

Design, assembly, and testing of the Tonne-Scale prototype of the DarkSide-20k detector for dark matter search with liquid Argon

Weakly Interacting Massive Particles (WIMPs) are among the leading candidates for dark matter (DM), potentially detectable via rare interactions with atomic nuclei. Direct detection relies on measuring the energy deposited when WIMPs scatter elastically off target atoms, producing nuclear recoils (NR). In liquid argon (LAr) detectors, these interactions generate scintillation light, which can be collected and analyzed to distinguish NRs from dominant electron recoils (ER) backgrounds usi...

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