The reaction of beta-silylated silyl ketene acetals with (ethoxycarbonylt)nitrene, generated by photolysis of N3CO2Et, produces beta-silylated N-(ethoxycarbonyl)-alpha-amino esters. The prevailing attack of the electrophile was always anti to the beta-silyl group in the substrates containing variously substituted chiral beta-carbon atoms. (C) 1997 Elsevier Science Ltd.
Amination of chiral beta-silylated silyl ketene acetals by (ethoxycarbonyl)nitrene / Loreto, Maria Antonietta; Tardella, Paolo Antonio; L., Tedeschi; D., Tofani. - In: TETRAHEDRON LETTERS. - ISSN 0040-4039. - STAMPA. - 38:32(1997), pp. 5717-5718. [10.1016/s0040-4039(97)01254-9]
Amination of chiral beta-silylated silyl ketene acetals by (ethoxycarbonyl)nitrene
LORETO, Maria Antonietta;TARDELLA, Paolo Antonio;
1997
Abstract
The reaction of beta-silylated silyl ketene acetals with (ethoxycarbonylt)nitrene, generated by photolysis of N3CO2Et, produces beta-silylated N-(ethoxycarbonyl)-alpha-amino esters. The prevailing attack of the electrophile was always anti to the beta-silyl group in the substrates containing variously substituted chiral beta-carbon atoms. (C) 1997 Elsevier Science Ltd.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
