BACKGROUND: The term "chemsex" was coined to indicate the voluntary intake of psychoactive and non psychoactive drugs in the context of recreational settings to facilitate and/or to enhance sexual intercourses mostly among men who have sex with other men (MSM). OBJECTIVE: The authors aimed to review the mechanisms of action, the toxicity and the pattern of use and abuse of substances involved in "chemsex" practice together with the sociocultural background underlying it and the health-related consequences that they may have. RESULTS: Gamma-hydroxybutyrate gamma-butyrolactone,1,4-butanediol, mephedrone, methamphetamine, sildenafil, tadalafil, vardenafil and alkyl nitrites have been described in their role of "chemsex drugs" including pharmacological action and in their implication to impair capacities to chose sexual partners and consensual sex. Moreover, it has been demonstrated that sexual activity over protracted length of time under the influence of chemsex drugs can result in rectal trauma or penile abrasions and a significant increase of the risk of transmission of sexual transmitted diseases, especially in case of condomless intercourses, which are frequent in this context, representing therefore a serious health threat. CONCLUSION: One of the major problems to establish health policy priority interventions for chemsex is the lack of available epidemiological and data on the issue. Finally, social actions should be taken in order to break down the barriers that currently exist among chemsex drug users in accessing services, including the shame and stigma often associated with drug use. In conclusion, more specific resources to face high risks of infections and HIV transmission are required in bisexual and homosexual individuals having SUID: sex under the influence of drugs.

When "chems" meet sex: a rising phenomenon called "ChemSex" / Giorgetti, Raffaele; Tagliabracci, Adriano; Schifano, Fabrizio; Zaami, Simona; Marinelli, Enrico; Busardo', FRANCESCO PAOLO. - In: CURRENT NEUROPHARMACOLOGY. - ISSN 1570-159X. - ELETTRONICO. - 15:5(2017), pp. 762-770. [10.2174/1570159X15666161117151148]

When "chems" meet sex: a rising phenomenon called "ChemSex"

ZAAMI, Simona;MARINELLI, Enrico;BUSARDO', FRANCESCO PAOLO
2017

Abstract

BACKGROUND: The term "chemsex" was coined to indicate the voluntary intake of psychoactive and non psychoactive drugs in the context of recreational settings to facilitate and/or to enhance sexual intercourses mostly among men who have sex with other men (MSM). OBJECTIVE: The authors aimed to review the mechanisms of action, the toxicity and the pattern of use and abuse of substances involved in "chemsex" practice together with the sociocultural background underlying it and the health-related consequences that they may have. RESULTS: Gamma-hydroxybutyrate gamma-butyrolactone,1,4-butanediol, mephedrone, methamphetamine, sildenafil, tadalafil, vardenafil and alkyl nitrites have been described in their role of "chemsex drugs" including pharmacological action and in their implication to impair capacities to chose sexual partners and consensual sex. Moreover, it has been demonstrated that sexual activity over protracted length of time under the influence of chemsex drugs can result in rectal trauma or penile abrasions and a significant increase of the risk of transmission of sexual transmitted diseases, especially in case of condomless intercourses, which are frequent in this context, representing therefore a serious health threat. CONCLUSION: One of the major problems to establish health policy priority interventions for chemsex is the lack of available epidemiological and data on the issue. Finally, social actions should be taken in order to break down the barriers that currently exist among chemsex drug users in accessing services, including the shame and stigma often associated with drug use. In conclusion, more specific resources to face high risks of infections and HIV transmission are required in bisexual and homosexual individuals having SUID: sex under the influence of drugs.
2017
chemsex; GHB; mephedrone; crystal meth; erectile dysfunction agents; viagra; poppers
01 Pubblicazione su rivista::01a Articolo in rivista
When "chems" meet sex: a rising phenomenon called "ChemSex" / Giorgetti, Raffaele; Tagliabracci, Adriano; Schifano, Fabrizio; Zaami, Simona; Marinelli, Enrico; Busardo', FRANCESCO PAOLO. - In: CURRENT NEUROPHARMACOLOGY. - ISSN 1570-159X. - ELETTRONICO. - 15:5(2017), pp. 762-770. [10.2174/1570159X15666161117151148]
File allegati a questo prodotto
File Dimensione Formato  
Giorgetti_When chems_2017.pdf

accesso aperto

Tipologia: Documento in Post-print (versione successiva alla peer review e accettata per la pubblicazione)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 1.54 MB
Formato Adobe PDF
1.54 MB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/909870
Citazioni
  • ???jsp.display-item.citation.pmc??? 47
  • Scopus 151
  • ???jsp.display-item.citation.isi??? 135
social impact