Magnetic resonance enterography in crohn's disease. new simple proposal to assess disease activity

PURPOSE: The aim is to determine the accuracy of magnetic resonance enterography (MRE) in evaluating Crohn's disease (CD) activity. MATERIALS AND METHODS: Seventy-seven patients with CD underwent MRE. The primary analysis was to determine associations between MRE findings, Harvey-Bradshaw Index, and C-reactive protein (CRP), then we have created a new MRE score that it was also correlated with clinical and laboratory data. RESULTS: MRE score for CD significantly correlates with CRP (P=.003). Significant associations were found between degree of contrast enhancement and CRP (P=.002) and between comb sign and CRP (P=.001). CONCLUSIONS: These results make MRE an important instrument for evaluation of CD activity. Copyright © 2016 Elsevier Inc. All rights reserved. KEYWORDS: Crohn’s disease; Inflammatory bowel disease; Magnetic resonance enterography score; Magnetic resonance imaging PMID: 27133693 DOI: 10.1016/j.clinimag.2015.11.009