We report the first analysis in absolute, and in particular, concerning the phytochemical pattern, about an endemic Italian species, Ajuga tenorei C. Presl. The analysis, performed by means of techniques such as Column Chromatography and NMR spectroscopy and Mass spectrometry, led to the isolation and the identification of five compounds namely verbascoside (1), echinacoside (2), ajugoside (3), harpagide (4) and 8-O-acetylharpagide (5). The presence of these compounds is important from both chemotaxonomic and ethno-pharmacological point of view. For what concerns the first point is confirmed the correct botanical classification of the species. The isolated compounds are also known to exert peculiar pharmacological activities and their presence may give a rationale to the historical medicinal properties associated to the Ajuga genus in general, since these plants have a long traditional use in many parts of the world. Such fact might suggest the use of also this species in this sense.

Iridoids and phenylethanoid glycosides from the aerial parts of Ajuga tenorei, an endemic Italian species / Frezza, Claudio; Venditti, Alessandro; Di Cecco, M; Ciaschetti, G; Serafini, Mauro; Bianco, Armandodoriano. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6427. - STAMPA. - 31:2(2016), pp. 218-223. [10.1080/14786419.2016.1218490]

Iridoids and phenylethanoid glycosides from the aerial parts of Ajuga tenorei, an endemic Italian species

FREZZA, CLAUDIO;VENDITTI, ALESSANDRO
;
SERAFINI, Mauro;BIANCO, Armandodoriano
2016

Abstract

We report the first analysis in absolute, and in particular, concerning the phytochemical pattern, about an endemic Italian species, Ajuga tenorei C. Presl. The analysis, performed by means of techniques such as Column Chromatography and NMR spectroscopy and Mass spectrometry, led to the isolation and the identification of five compounds namely verbascoside (1), echinacoside (2), ajugoside (3), harpagide (4) and 8-O-acetylharpagide (5). The presence of these compounds is important from both chemotaxonomic and ethno-pharmacological point of view. For what concerns the first point is confirmed the correct botanical classification of the species. The isolated compounds are also known to exert peculiar pharmacological activities and their presence may give a rationale to the historical medicinal properties associated to the Ajuga genus in general, since these plants have a long traditional use in many parts of the world. Such fact might suggest the use of also this species in this sense.
2016
Ajuga tenorei C. Presl; chemotaxonomy; ethno-pharmacology; iridoids; phenyl-ethanoid glycosides
01 Pubblicazione su rivista::01a Articolo in rivista
Iridoids and phenylethanoid glycosides from the aerial parts of Ajuga tenorei, an endemic Italian species / Frezza, Claudio; Venditti, Alessandro; Di Cecco, M; Ciaschetti, G; Serafini, Mauro; Bianco, Armandodoriano. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6427. - STAMPA. - 31:2(2016), pp. 218-223. [10.1080/14786419.2016.1218490]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/903568
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