It has been suggested that phosphodiesterase 5 (PDE5) inhibition is potentially hazardous and that it increases the risk of cardiac events in patients with coronary artery disease. This study sought to evaluate whether PDE5 inhibition with sildenafil exerts any effect on exercise-induced myocardial ischemia in patients on beta-blockers.

Effect of sildenafil citrate upon myocardial ischemia in patients with chronic stable angina in therapy with beta-blockers / Patrizi, R; Leonardo, F; Pelliccia, Francesco; Chierchia, S. L; Galetta, P; Cerquetani, E; Frascà, F; Fini, M; Rosano, G. M.. - In: ITALIAN HEART JOURNAL. - ISSN 1129-471X. - STAMPA. - 2:11(2001), p. 841-4.

Effect of sildenafil citrate upon myocardial ischemia in patients with chronic stable angina in therapy with beta-blockers

PELLICCIA, FRANCESCO;
2001

Abstract

It has been suggested that phosphodiesterase 5 (PDE5) inhibition is potentially hazardous and that it increases the risk of cardiac events in patients with coronary artery disease. This study sought to evaluate whether PDE5 inhibition with sildenafil exerts any effect on exercise-induced myocardial ischemia in patients on beta-blockers.
2001
Adrenergic beta-Antagonists; Adult; Aged; Angina Pectoris; Atenolol; Blood Pressure; Chronic Disease; Drug Interactions; Exercise Test; Heart Rate; Humans; Male; Middle Aged; Myocardial Ischemia; Phosphodiesterase Inhibitors; Piperazines; Purines; Sildenafil Citrate; Sulfones
01 Pubblicazione su rivista::01a Articolo in rivista
Effect of sildenafil citrate upon myocardial ischemia in patients with chronic stable angina in therapy with beta-blockers / Patrizi, R; Leonardo, F; Pelliccia, Francesco; Chierchia, S. L; Galetta, P; Cerquetani, E; Frascà, F; Fini, M; Rosano, G. M.. - In: ITALIAN HEART JOURNAL. - ISSN 1129-471X. - STAMPA. - 2:11(2001), p. 841-4.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/897002
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