Progressive supranuclear palsy (PSP) is a rare form of parkinsonism. The incidence rates are about 0.3-1.1 cases per 100,000 persons. The only two case-control studies performed up to now show conflictual results as regards education and residence in rural areas. Recently, a cluster of PSP and atypical parkinsonism has been observed in French Antilles. The hypothesis is that a consumption of both tropical fruit and herbal tea may be associated with PSP onset. Some PSP families with a probably autosomal dominant transmission have been described. A high frequency of a tau haplotype (H1/H1) associated with PSP is reported by some authors. The significance of this association is still not clear. We have performed a case-control study on 58 PSP cases, 116 hospital controls and 58 population controls.

Epidemiology of progressive supranuclear palsy. ESGAP Consortium. European Study Group on Atypical Parkinsonisms / Vanacore, Nicola; Bonifati, Vincenzo; Colosimo, Carlo; Fabbrini, Giovanni; De Michele, G; Marconi, R; Nicholl, D; Locuratolo, Nicoletta; Romano, Silvia; Talarico, Giuseppina; Stocchi, F; Bonuccelli, U; Lamberti, P; Vieregge, P; Meco, Giuseppe. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - 22:1(2001), p. 101-3.

Epidemiology of progressive supranuclear palsy. ESGAP Consortium. European Study Group on Atypical Parkinsonisms

VANACORE, NICOLA;BONIFATI, Vincenzo;COLOSIMO, Carlo;FABBRINI, Giovanni;LOCURATOLO, NICOLETTA;ROMANO, SILVIA;TALARICO, GIUSEPPINA;MECO, Giuseppe
2001

Abstract

Progressive supranuclear palsy (PSP) is a rare form of parkinsonism. The incidence rates are about 0.3-1.1 cases per 100,000 persons. The only two case-control studies performed up to now show conflictual results as regards education and residence in rural areas. Recently, a cluster of PSP and atypical parkinsonism has been observed in French Antilles. The hypothesis is that a consumption of both tropical fruit and herbal tea may be associated with PSP onset. Some PSP families with a probably autosomal dominant transmission have been described. A high frequency of a tau haplotype (H1/H1) associated with PSP is reported by some authors. The significance of this association is still not clear. We have performed a case-control study on 58 PSP cases, 116 hospital controls and 58 population controls.
2001
Age of Onset; Beverages; Environmental Exposure; Female; Genetic Testing; Guadeloupe; Humans; Incidence; Male; Mutation; Occupational Diseases; Prevalence; Risk Factors; Sex Factors; Supranuclear Palsy, Progressive; tau Proteins
01 Pubblicazione su rivista::01a Articolo in rivista
Epidemiology of progressive supranuclear palsy. ESGAP Consortium. European Study Group on Atypical Parkinsonisms / Vanacore, Nicola; Bonifati, Vincenzo; Colosimo, Carlo; Fabbrini, Giovanni; De Michele, G; Marconi, R; Nicholl, D; Locuratolo, Nicoletta; Romano, Silvia; Talarico, Giuseppina; Stocchi, F; Bonuccelli, U; Lamberti, P; Vieregge, P; Meco, Giuseppe. - In: NEUROLOGICAL SCIENCES. - ISSN 1590-1874. - 22:1(2001), p. 101-3.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/895010
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