Imatinib mesylate (IM) represents the first-line treatment of patients with chronic myeloid leukemia (CLM) or gastrointestinal stromal tumor (GIST). It presents several side effects. However, less than 10% are nonhematologic including nausea, vomiting, diarrhea, muscle cramps, and cutaneous reactions. The aim of our study was to identify data regarding IM cutaneous adverse effects (AEs) to improve the clinical diagnosis and management of the more frequent side effects. Skin examination should be done before and during IM treatment so that AEs can be diagnosed and treated early with less impact on chemotherapy treatments and on the quality of life of the patient.
Imatinib mesylate (IM) represents the first-line treatment of patients with chronic myeloid leukemia (CLM) or gastrointestinal stromal tumor (GIST). It presents several side effects. However, less than 10% are nonhematologic including nausea, vomiting, diarrhea, muscle cramps, and cutaneous reactions. The aim of our study was to identify data regarding IM cutaneous adverse effects (AEs) to improve the clinical diagnosis and management of the more frequent side effects. Skin examination should be done before and during IM treatment so that AEs can be diagnosed and treated early with less impact on chemotherapy treatments and on the quality of life of the patient.
Skin lesions in patients treated with imatinib mesylate: a 5-year prospective study / Paolino, Giovanni; Didona, D; Clerico, Rita; Corsetti, Paola; Ambrifi, Marina; Bottoni, Ugo; Calvieri, Stefano. - In: CUTIS. - ISSN 0011-4162. - (2016).
Skin lesions in patients treated with imatinib mesylate: a 5-year prospective study
paolino, giovanni;CLERICO, Rita;CORSETTI, PAOLA;AMBRIFI, MARINA;BOTTONI, Ugo;CALVIERI, Stefano
2016
Abstract
Imatinib mesylate (IM) represents the first-line treatment of patients with chronic myeloid leukemia (CLM) or gastrointestinal stromal tumor (GIST). It presents several side effects. However, less than 10% are nonhematologic including nausea, vomiting, diarrhea, muscle cramps, and cutaneous reactions. The aim of our study was to identify data regarding IM cutaneous adverse effects (AEs) to improve the clinical diagnosis and management of the more frequent side effects. Skin examination should be done before and during IM treatment so that AEs can be diagnosed and treated early with less impact on chemotherapy treatments and on the quality of life of the patient.| File | Dimensione | Formato | |
|---|---|---|---|
|
Paolino_Skin lesions_2016.pdf
solo utenti autorizzati
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
1.36 MB
Formato
Adobe PDF
|
1.36 MB | Adobe PDF | Contatta l'autore |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
