Introduction. Alcoholic hepatitis (AH) is an acute-on-chronic inflammatory response affecting the liver. It has been recognized that white blood cells (WBCs) are involved in the pathogenesis and in the prognosis of AH. The aim of study was to use Adacolumn, which can selectively adsorb myeloid linage leucocytes (granulocytes and monocytes/ macrophages) from the blood in the column and improve the clinical status of patients Conclusions. The Adacolumn apheresis was safe and was able to determine an improvement of clinical status of patients with reduction of inflammatory markers. More patients are needed to validate these results.

Alcoholic hepatitis (AH) is an acute-on-chronic inflammatory response affecting the liver. It has been recognized that white blood cells (WBCs) are involved in the pathogenesis and in the prognosis of AH. The aim of study was to use Adacolumn, which can selectively adsorb myeloid linage leucocytes (granulocytes and monocytes/macrophages) from the blood in the column and improve the clinical status of patients.

Adacolumn granulocyte-apheresis for alcoholic hepatitis. Preliminary study / Morabito, VINCENZO EMILIANO; Novelli, Simone; Poli, Luca; Ferretti, G; Ruberto, F; Pugliese, Francesco; Pretagostini, Renzo; Berloco, P. B; Rossi, Massimo. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - STAMPA. - 48:2(2016), pp. 352-358. [10.1016/j.transproceed.2015.12.055]

Adacolumn granulocyte-apheresis for alcoholic hepatitis. Preliminary study

MORABITO, VINCENZO EMILIANO;NOVELLI, SIMONE;POLI, Luca;PUGLIESE, Francesco;PRETAGOSTINI, Renzo;ROSSI, MASSIMO
2016

Abstract

Alcoholic hepatitis (AH) is an acute-on-chronic inflammatory response affecting the liver. It has been recognized that white blood cells (WBCs) are involved in the pathogenesis and in the prognosis of AH. The aim of study was to use Adacolumn, which can selectively adsorb myeloid linage leucocytes (granulocytes and monocytes/macrophages) from the blood in the column and improve the clinical status of patients.
Introduction. Alcoholic hepatitis (AH) is an acute-on-chronic inflammatory response affecting the liver. It has been recognized that white blood cells (WBCs) are involved in the pathogenesis and in the prognosis of AH. The aim of study was to use Adacolumn, which can selectively adsorb myeloid linage leucocytes (granulocytes and monocytes/ macrophages) from the blood in the column and improve the clinical status of patients Conclusions. The Adacolumn apheresis was safe and was able to determine an improvement of clinical status of patients with reduction of inflammatory markers. More patients are needed to validate these results.
Adacolumn, Granulocyte-Apheresis, Alcoholic Hepatitis
01 Pubblicazione su rivista::01a Articolo in rivista
Adacolumn granulocyte-apheresis for alcoholic hepatitis. Preliminary study / Morabito, VINCENZO EMILIANO; Novelli, Simone; Poli, Luca; Ferretti, G; Ruberto, F; Pugliese, Francesco; Pretagostini, Renzo; Berloco, P. B; Rossi, Massimo. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - STAMPA. - 48:2(2016), pp. 352-358. [10.1016/j.transproceed.2015.12.055]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/878689
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