We investigate the characteristic time-scales for swelling and drug release from polymeric thin films for buccal delivery. In this work, novel OTFs were prepared combining Gellan gum, a natural polysaccharide well known in the pharmaceutical field, along with Glycerol, used as plasticizer. A new millifluidic flow-through device is adopted for in-vitro release tests.
Swelling and drug release from oral thin films (OTFs) / Adrover, Alessandra; Casadei, Maria Antonietta; Paolicelli, Patrizia; Petralito, Stefania; Varani, Gabriele. - STAMPA. - 1736:(2016). ( 8th International conference on times of polymers and composites. From aerospace to nanotechnology Naples, Italy 19–23 June 2016) [10.1063/1.4949660].
Swelling and drug release from oral thin films (OTFs)
ADROVER, Alessandra
Primo
;CASADEI, Maria Antonietta;PAOLICELLI, PATRIZIA;PETRALITO, Stefania;VARANI, GABRIELE
2016
Abstract
We investigate the characteristic time-scales for swelling and drug release from polymeric thin films for buccal delivery. In this work, novel OTFs were prepared combining Gellan gum, a natural polysaccharide well known in the pharmaceutical field, along with Glycerol, used as plasticizer. A new millifluidic flow-through device is adopted for in-vitro release tests.| File | Dimensione | Formato | |
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