This study aimed to investigate the effects of a nutraceutical composition on the expression of some genes involved in muscle cells and functioning in osteoblast cells. The effects of nutraceutical composition have been compared to the effects of atorvastatin, which induces muscle pain and elevated creatine phosphokinase (CPK) serum level when administered to patients. In particular, we analyzed the MyoD-1 gene, which is responsible for modulation of the CPK gene, which is a marker of muscle pain and damage
A nutraceutical composition decreases cpk levels in saos-2 cells and in patients with elevated serum levels of this enzyme / Ammendola, Sergio; Stoppoloni, Daniela; Di Loreto, Mario; SCOTTO D'ABUSCO, Anna. - In: JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION. - ISSN 0731-5724. - STAMPA. - 35:(2016), pp. 559-567. [10.1080/07315724.2015.1093972]
A nutraceutical composition decreases cpk levels in saos-2 cells and in patients with elevated serum levels of this enzyme
SCOTTO D'ABUSCO, ANNA
2016
Abstract
This study aimed to investigate the effects of a nutraceutical composition on the expression of some genes involved in muscle cells and functioning in osteoblast cells. The effects of nutraceutical composition have been compared to the effects of atorvastatin, which induces muscle pain and elevated creatine phosphokinase (CPK) serum level when administered to patients. In particular, we analyzed the MyoD-1 gene, which is responsible for modulation of the CPK gene, which is a marker of muscle pain and damage| File | Dimensione | Formato | |
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Ammendola_A Nutraceutical _2016
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