The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs. There are many categories of NPS, such as synthetic cannabinoids, synthetic cathinones, phenylethylamines, piperazines, ketamine derivatives and tryptamines. Tryptamines are naturally occurring compounds, which can derive from the amino acid tryptophan by several biosynthetic pathways: their structure is a combination of a benzene ring and a pyrrole ring, with the addition of a 2-carbon side chain. Tryptamines include serotonin and melatonin as well as other compounds known for their hallucinogenic properties, such as psilocybin in 'Magic mushrooms' and dimethyltryptamine (DMT) in Ayahuasca brews.

Recreational use, analysis and toxicity of tryptamines / Tittarelli, Roberta; Mannocchi, Giulio; Pantano, Flaminia; Romolo, Francesco Saverio. - In: CURRENT NEUROPHARMACOLOGY. - ISSN 1570-159X. - ELETTRONICO. - 13:1(2015), pp. 26-46. [10.2174/1570159X13666141210222409]

Recreational use, analysis and toxicity of tryptamines

TITTARELLI, ROBERTA;MANNOCCHI, Giulio;PANTANO, FLAMINIA;ROMOLO, Francesco Saverio
2015

Abstract

The definition New psychoactive substances (NPS) refers to emerging drugs whose chemical structures are similar to other psychoactive compounds but not identical, representing a "legal" alternative to internationally controlled drugs. There are many categories of NPS, such as synthetic cannabinoids, synthetic cathinones, phenylethylamines, piperazines, ketamine derivatives and tryptamines. Tryptamines are naturally occurring compounds, which can derive from the amino acid tryptophan by several biosynthetic pathways: their structure is a combination of a benzene ring and a pyrrole ring, with the addition of a 2-carbon side chain. Tryptamines include serotonin and melatonin as well as other compounds known for their hallucinogenic properties, such as psilocybin in 'Magic mushrooms' and dimethyltryptamine (DMT) in Ayahuasca brews.
2015
clinical effects; emergency departments; fatalities; forensic toxicology; intoxication; new psychoactive substances (NPS); tryptamines.; designer drugs; humans; poisoning; psychotropic drugs; street drugs; structure-activity relationship; substance-related disorders; tryptamines
01 Pubblicazione su rivista::01a Articolo in rivista
Recreational use, analysis and toxicity of tryptamines / Tittarelli, Roberta; Mannocchi, Giulio; Pantano, Flaminia; Romolo, Francesco Saverio. - In: CURRENT NEUROPHARMACOLOGY. - ISSN 1570-159X. - ELETTRONICO. - 13:1(2015), pp. 26-46. [10.2174/1570159X13666141210222409]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/874462
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