Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.
Merkel cell carcinoma of the retroperitoneum with no identifiable primary site / Rossini, Daniele; Caponnetto, Salvatore; Lapadula, Vittoria; DE FILIPPIS, Lucilla; DEL BENE, Gabriella; Emiliani, Alessandra; Longo, Flavia. - In: CASE REPORTS IN ONCOLOGICAL MEDICINE. - ISSN 2090-6706. - 2013:(2013), pp. 131695-3. [10.1155/2013/131695]
Merkel cell carcinoma of the retroperitoneum with no identifiable primary site
CAPONNETTO, SALVATORE;LAPADULA, VITTORIA;DE FILIPPIS, LUCILLA;DEL BENE, GABRIELLA;EMILIANI, ALESSANDRA;
2013
Abstract
Merkel cell carcinoma (MCC) is an extremely rare primary neuroendocrine neoplasm of the skin that shows aggressive behavior and a poor prognosis. We report a case of a 67-year-old male with a Merkel cell carcinoma which initially presented itself as a large retroperitoneal mass. Pathological and immunohistochemical analysis revealed tissue consistent with neuroendocrine carcinoma. Despite complete medical workup, no other primary MCC could be detected. While being an atypical presentation, the tumor mass showed an excellent response to the combination of chemotherapy followed by radiotherapy.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
