Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field showed a reorganization of membrane and cytoskeletal components. Atomic force microscopy in air revealed several modifications in 80% of the exposed cells, such as loss of microvilli-like structures followed by progressive appearance of membrane introflections. This change in plasma membrane morphology was also accompanied by a different actin distribution, as detected by phalloidin fluorescence. These observations support our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure. (C) 2000 Wiley-Liss,Inc.
Three dimensional (3D) analysis of the morphological changes induced by 50 Hz magnetic field exposure on human lymphoblastoid cells (Raji) / A., Lisi; Pozzi, Deleana; E., Pasquali; S., Rieti; M., Girasole; V., Manni; M., Cricenti; R., Generosi; Serafino, Al; A., Congiu Castellano; G., Ravagnan; S., Grimaldi. - In: BIOELECTROMAGNETICS. - ISSN 0197-8462. - STAMPA. - 21:1(2000), pp. 46-51. [10.1002/(sici)1521-186x(200001)21:1<46::aid-bem7>3.0.co;2-z]
Three dimensional (3D) analysis of the morphological changes induced by 50 Hz magnetic field exposure on human lymphoblastoid cells (Raji)
POZZI, Deleana;
2000
Abstract
Human Raji B lymphoid cells after exposure for 64 h to a 1 mT (rms) 50 Hz sinusoidal magnetic field showed a reorganization of membrane and cytoskeletal components. Atomic force microscopy in air revealed several modifications in 80% of the exposed cells, such as loss of microvilli-like structures followed by progressive appearance of membrane introflections. This change in plasma membrane morphology was also accompanied by a different actin distribution, as detected by phalloidin fluorescence. These observations support our previous hypothesis that electric and magnetic fields may modify the plasma membrane structure. (C) 2000 Wiley-Liss,Inc.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
