Abdominal surgical site infection due to Klebsiella pneumoniae carbapenemase-producing K. pneumoniae

.The spread of bacteria extensively resistant to multiple antibiotics is becoming an unprecedented public health concern. Different from multidrug-resistant (MDR) Gram-positive pathogens, for which new antibiotics (such as new glycopeptides and oxazolidinones) have already been approved in virtue of high efficacy, the situation surrounding MDR Gram-negative bacteria, such as those belonging to the Enterobacteriaceae family, appears more critical because of the very limited choice of available antibiotics and the absence of new successful molecules. In particular, Gram-negative K. pneumoniae carbapenemase (KPC)-producing K. pneumoniae (KPC-Kp) recently emerged as one of the most worrisome germs causing health care associated infections (HAI) with a poor prognosis in the immediate post-operative period, especially after emergency abdominal surgery.