Objectives To prospectively investigate the pre and intraprocedural risk factors for immediate (IF) and delayedonset (DOF) fever development after percutaneous transhepatic biliary drainage (PTBD). Methods Institutional review board approval and informed patient consent were obtained. Between February 2013 and February 2014, 97 afebrile patients (77 at the Sapienza University of Rome, Italy and 20 at the Sun Yatsen University of Guangzhou, China) with benign (n = 31) and malignant (n = 66) indications for a first PTBD were prospectively enrolled. Thirty pre- and intra-procedural clinical/radiological characteristics, including the amount of contrast media injected prior to PTBD placement, were collected in relation to the development of IF (within 24 h) or DOF (after 24 h). Fever was defined as C37.5 C. Binary logistic regression analysis was used to assess independent associations with IF and DOF. Results Fourteen (14.4 %) patients developed IF and 17 (17.5 %) developed DOF. At multivariable analysis, IF was associated with pre-procedural absence of intrahepatic bile duct dilatation (OR 63.359; 95 % CI 2.658–1510.055; P = 0.010) and low INR (OR 4.7 9 10-4 ; 95 % CI 0.000–0.376; P = 0.025), while DOF was associated with unsatisfactory biliary drainage at the end of PTBD (OR 4.571; 95 % CI 1.161–17.992; P = 0.030).

Risk factors for immediate and delayed-onset fever after percutaneous transhepatic biliary drainage / Lucatelli, Pierleone; GINANNI CORRADINI, Stefano; Corona, Mario; GINANNI CORRADINI, Luca; Cirelli, Carlo; Saba, Luca; Poli, Edoardo; Fanelli, Fabrizio; Wang, Haofan; Bezzi, Mario; Catalano, Carlo. - In: CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. - ISSN 0174-1551. - STAMPA. - 39:5(2016), pp. 746-755. [10.1007/s00270-015-1242-9]

Risk factors for immediate and delayed-onset fever after percutaneous transhepatic biliary drainage

Pierleone Lucatelli
Primo
;
Stefano Ginanni Corradini
Secondo
;
Luca Ginanni Corradini;Carlo Cirelli;Edoardo Poli;Fabrizio Fanelli;Mario Bezzi
Penultimo
;
Carlo Catalano
Ultimo
2016

Abstract

Objectives To prospectively investigate the pre and intraprocedural risk factors for immediate (IF) and delayedonset (DOF) fever development after percutaneous transhepatic biliary drainage (PTBD). Methods Institutional review board approval and informed patient consent were obtained. Between February 2013 and February 2014, 97 afebrile patients (77 at the Sapienza University of Rome, Italy and 20 at the Sun Yatsen University of Guangzhou, China) with benign (n = 31) and malignant (n = 66) indications for a first PTBD were prospectively enrolled. Thirty pre- and intra-procedural clinical/radiological characteristics, including the amount of contrast media injected prior to PTBD placement, were collected in relation to the development of IF (within 24 h) or DOF (after 24 h). Fever was defined as C37.5 C. Binary logistic regression analysis was used to assess independent associations with IF and DOF. Results Fourteen (14.4 %) patients developed IF and 17 (17.5 %) developed DOF. At multivariable analysis, IF was associated with pre-procedural absence of intrahepatic bile duct dilatation (OR 63.359; 95 % CI 2.658–1510.055; P = 0.010) and low INR (OR 4.7 9 10-4 ; 95 % CI 0.000–0.376; P = 0.025), while DOF was associated with unsatisfactory biliary drainage at the end of PTBD (OR 4.571; 95 % CI 1.161–17.992; P = 0.030).
2016
bile duct dilatation; contrast media volume; fever; percutaneous transhepatic biliary drainage; unsatisfactory biliary drainage; radiology, nuclear medicine and imaging; cardiology and cardiovascular medicine
01 Pubblicazione su rivista::01a Articolo in rivista
Risk factors for immediate and delayed-onset fever after percutaneous transhepatic biliary drainage / Lucatelli, Pierleone; GINANNI CORRADINI, Stefano; Corona, Mario; GINANNI CORRADINI, Luca; Cirelli, Carlo; Saba, Luca; Poli, Edoardo; Fanelli, Fabrizio; Wang, Haofan; Bezzi, Mario; Catalano, Carlo. - In: CARDIOVASCULAR AND INTERVENTIONAL RADIOLOGY. - ISSN 0174-1551. - STAMPA. - 39:5(2016), pp. 746-755. [10.1007/s00270-015-1242-9]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/851444
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