Migraine is the most prevalent neurological disorder worldwide and ranked sixth among all diseases in years lived with disability. Overall preventive anti-migraine therapies have an effect in one patient out of two at the most, many of them being endowed with disabling adverse effects. No new disease-modifying drugs have come into clinical practice since the application to migraine of topiramate and botulinum toxin, the latter for its chronic form. There is thus clearly a need for more effective treatments that are devoid of, or have acceptable side effects. In recent years, scientific progress in migraine research has led to substantial changes in our understanding of the pathophysiology of migraine and paved the way for novel non-drug pathophysiological-targeted treatment strategies.

Pathophysiological targets for non-pharmacological treatment of migraine / Coppola, Gianluca; DI LORENZO, Cherubino; Serrao, Mariano; Parisi, Vincenzo; Schoenen, Jean; Pierelli, Francesco. - In: CEPHALALGIA. - ISSN 0333-1024. - ELETTRONICO. - 36:12(2016), pp. 1103-1111. [10.1177/0333102415620908]

Pathophysiological targets for non-pharmacological treatment of migraine

COPPOLA, GIANLUCA;DI LORENZO, CHERUBINO;SERRAO, Mariano;PIERELLI, Francesco
2016

Abstract

Migraine is the most prevalent neurological disorder worldwide and ranked sixth among all diseases in years lived with disability. Overall preventive anti-migraine therapies have an effect in one patient out of two at the most, many of them being endowed with disabling adverse effects. No new disease-modifying drugs have come into clinical practice since the application to migraine of topiramate and botulinum toxin, the latter for its chronic form. There is thus clearly a need for more effective treatments that are devoid of, or have acceptable side effects. In recent years, scientific progress in migraine research has led to substantial changes in our understanding of the pathophysiology of migraine and paved the way for novel non-drug pathophysiological-targeted treatment strategies.
2016
non-pharmacological treatment; diets; migraine pathophysiology; neurostimulation; nutraceuticals
01 Pubblicazione su rivista::01a Articolo in rivista
Pathophysiological targets for non-pharmacological treatment of migraine / Coppola, Gianluca; DI LORENZO, Cherubino; Serrao, Mariano; Parisi, Vincenzo; Schoenen, Jean; Pierelli, Francesco. - In: CEPHALALGIA. - ISSN 0333-1024. - ELETTRONICO. - 36:12(2016), pp. 1103-1111. [10.1177/0333102415620908]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/845696
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