Pharmacological enhancement of 5-hydroxytryptamine (5-HT) transmission increases plasma vasopressin in rats. To investigate whether this effect is mediated through activation of the peripheral renin-angiotensin system, plasma vasopressin concentrations were measured after 5-HT activation in rats with lesions of the subfornical organ or pretreated with saralasin. The results show that the 5-HT-induced elevation of vasopressin is not due to activation of the peripheral renin-angiotensin system.
VASOPRESSIN RELEASE AFTER ENHANCED SEROTONERGIC TRANSMISSION IS NOT DUE TO ACTIVATION OF THE PERIPHERAL RENIN-ANGIOTENSIN SYSTEM / Steardo, Luca; Michele, Iovino. - In: BRAIN RESEARCH. - ISSN 0006-8993. - STAMPA. - 382:1(1986), pp. 145-148. [10.1016/0006-8993(86)90122-8]
VASOPRESSIN RELEASE AFTER ENHANCED SEROTONERGIC TRANSMISSION IS NOT DUE TO ACTIVATION OF THE PERIPHERAL RENIN-ANGIOTENSIN SYSTEM
STEARDO, LUCA;
1986
Abstract
Pharmacological enhancement of 5-hydroxytryptamine (5-HT) transmission increases plasma vasopressin in rats. To investigate whether this effect is mediated through activation of the peripheral renin-angiotensin system, plasma vasopressin concentrations were measured after 5-HT activation in rats with lesions of the subfornical organ or pretreated with saralasin. The results show that the 5-HT-induced elevation of vasopressin is not due to activation of the peripheral renin-angiotensin system.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
