Lesions of septal nuclei in rats enhance water intake and urine outflow. The effects of nicotine tartrate (2.5 mg/kg) on drinking and diuresis were investigated in normal, sham and septal lesioned rats. Nicotine administration resulted in a surprising hyperdipsia and polyuria in lesioned animals, the mean output rose from 38 ± 1.3 ml (before treatment) to 101.6 ± 6.1 (during treatment) and water intake increased from 74.2 ±1.8 ml to 129.8 ± 6.4 ml. © 1985.
Effect of nicotine on drinking and diuresis in septal lesioned rats / M., Iovino; P., Monteleone; Steardo, Luca. - In: PHYSIOLOGY & BEHAVIOR. - ISSN 0031-9384. - STAMPA. - 34:2(1985), pp. 307-309. [10.1016/0031-9384(85)90120-9]
Effect of nicotine on drinking and diuresis in septal lesioned rats
STEARDO, LUCA
1985
Abstract
Lesions of septal nuclei in rats enhance water intake and urine outflow. The effects of nicotine tartrate (2.5 mg/kg) on drinking and diuresis were investigated in normal, sham and septal lesioned rats. Nicotine administration resulted in a surprising hyperdipsia and polyuria in lesioned animals, the mean output rose from 38 ± 1.3 ml (before treatment) to 101.6 ± 6.1 (during treatment) and water intake increased from 74.2 ±1.8 ml to 129.8 ± 6.4 ml. © 1985.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
