The effect of the GABAergic drug sodium valproate (SV) on the exercise-induced release of growth hormone (GH) was investigated in 10 healthy males. The exercise test consisted of using a stationary bicycle ergometer at 450 kg/min for 20 min. SV 600 mg blunted the increase in GH induced by the exercise, suggesting GABAergic regulation of GH secretion in man, at least under certain physiological conditions. © 1985 Springer-Verlag.
EVIDENCE FOR A GABAERGIC CONTROL OF THE EXERCISE-INDUCED RISE IN GH IN MAN / Steardo, Luca; M., Iovino; P., Monteleone; M., Agrusta; F., Orio. - In: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. - ISSN 0031-6970. - STAMPA. - 28:5(1985), pp. 607-609. [10.1007/bf00544075]
EVIDENCE FOR A GABAERGIC CONTROL OF THE EXERCISE-INDUCED RISE IN GH IN MAN
STEARDO, LUCA;
1985
Abstract
The effect of the GABAergic drug sodium valproate (SV) on the exercise-induced release of growth hormone (GH) was investigated in 10 healthy males. The exercise test consisted of using a stationary bicycle ergometer at 450 kg/min for 20 min. SV 600 mg blunted the increase in GH induced by the exercise, suggesting GABAergic regulation of GH secretion in man, at least under certain physiological conditions. © 1985 Springer-Verlag.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.