Microwave thermal ablation (MTA) therapies exploit the local absorption of an electromagnetic field at microwave (MW) frequencies to destroy unhealthy tissue, by way of a very high temperature increase (about 60 °C or higher). To develop reliable interventional protocols, numerical tools able to correctly foresee the temperature increase obtained in the tissue would be very useful. In this work, different numerical models of the dielectric and thermal property changes with temperature were investigated, looking at the simulated temperature increments and at the size of the achievable zone of ablation. To assess the numerical data, measurement of the temperature increases close to a MTA antenna were performed in correspondence with the antenna feed-point and the antenna cooling system, for increasing values of the radiated power. Results show that models not including the changes of the dielectric and thermal properties can be used only for very low values of the power radiated by the antenna, whereas a good agreement with the experimental values can be obtained up to 20 W if water vaporization is included in the numerical model. Finally, for higher power values, a simulation that dynamically includes the tissue's dielectric and thermal property changes with the temperature should be performed.
Numerical models to evaluate the temperature increase induced by ex vivo microwave thermal ablation / Cavagnaro, Marta; Pinto, R.; Lopresto, V.. - In: PHYSICS IN MEDICINE AND BIOLOGY. - ISSN 0031-9155. - STAMPA. - 60:8(2015), pp. 3287-3311. [10.1088/0031-9155/60/8/3287]
Numerical models to evaluate the temperature increase induced by ex vivo microwave thermal ablation
CAVAGNARO, Marta;
2015
Abstract
Microwave thermal ablation (MTA) therapies exploit the local absorption of an electromagnetic field at microwave (MW) frequencies to destroy unhealthy tissue, by way of a very high temperature increase (about 60 °C or higher). To develop reliable interventional protocols, numerical tools able to correctly foresee the temperature increase obtained in the tissue would be very useful. In this work, different numerical models of the dielectric and thermal property changes with temperature were investigated, looking at the simulated temperature increments and at the size of the achievable zone of ablation. To assess the numerical data, measurement of the temperature increases close to a MTA antenna were performed in correspondence with the antenna feed-point and the antenna cooling system, for increasing values of the radiated power. Results show that models not including the changes of the dielectric and thermal properties can be used only for very low values of the power radiated by the antenna, whereas a good agreement with the experimental values can be obtained up to 20 W if water vaporization is included in the numerical model. Finally, for higher power values, a simulation that dynamically includes the tissue's dielectric and thermal property changes with the temperature should be performed.File | Dimensione | Formato | |
---|---|---|---|
Cavagnaro_Numerical-models_pre-print_2015.pdf
solo utenti autorizzati
Note: pre-print autore
Tipologia:
Documento in Pre-print (manoscritto inviato all'editore, precedente alla peer review)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
842.88 kB
Formato
Adobe PDF
|
842.88 kB | Adobe PDF | Contatta l'autore |
Cavagnaro_Numerical-models_2015.pdf
solo gestori archivio
Tipologia:
Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza:
Tutti i diritti riservati (All rights reserved)
Dimensione
2.02 MB
Formato
Adobe PDF
|
2.02 MB | Adobe PDF | Contatta l'autore |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.