Cancer treatment is performed, in Particle Therapy, using accelerated charged particles whose high irradiation precision and conformity allows the tumor destruction while sparing the surrounding healthy tissues. Dose release monitoring devices using photons and charged particles produced by the beam interaction with the patient body have already been proposed, but no attempt based on the detection of the abundant secondary radiation neutron component has been made yet. The reduced attenuation length of neutrons yields a secondary particle sample that is larger in number when compared to photons and charged particles. Furthermore, neutrons allow for a backtracking of the emission point that is not affected by multiple scattering. Since neutrons can release a significant dose far away from the tumor region, a precise measurement of their flux, production energy and angle distributions is eagerly needed in order to improve the Treatment Planning Systems (TPS) software, so to predict not only the normal tissue toxicity in the target region but also the risk of late complications in the whole body. All the aforementioned issues underline the importance for an experimental effort devoted to the precise characterization of the neutron production gaining experimental access both to the emission point and production energy. The technical challenges posed by a neutron detector aiming for a high detection efficiency and good backtracking precision will be addressed within the MONDO (MOnitor for Neutron Dose in hadrOntherapy) project. The MONDO's main goal is to develop a tracking detector targeting fast and ultrafast secondary neutrons. The tracker is composed by a scintillating fiber matrix ð4 4 8 cm3Þ. The full reconstruction of protons, produced in elastic interactions, will be used to measure energy and direction of the impinging neutron. The neutron tracker will measure the neutron production yields, as a function of production angle and energy, using different therapeutic beams at CNAO in Pavia (protons, 12C ions and possibly 4He and 16O ions).

MONDO: A neutron tracker for particle therapy secondary emission fluxes measurements / Marafini, M.; Patera, Vincenzo; Pinci, D.; Sarti, Alessio; Sciubba, Adalberto; Spiriti, E.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - (2015). (Intervento presentato al convegno Frontiers Detectors for Frontier Physics 13th Pisa Meeting on Advanced Detectors tenutosi a Elba) [10.1016/j.nima.2015.10.109].

MONDO: A neutron tracker for particle therapy secondary emission fluxes measurements

PATERA, Vincenzo;SARTI, ALESSIO;SCIUBBA, Adalberto;
2015

Abstract

Cancer treatment is performed, in Particle Therapy, using accelerated charged particles whose high irradiation precision and conformity allows the tumor destruction while sparing the surrounding healthy tissues. Dose release monitoring devices using photons and charged particles produced by the beam interaction with the patient body have already been proposed, but no attempt based on the detection of the abundant secondary radiation neutron component has been made yet. The reduced attenuation length of neutrons yields a secondary particle sample that is larger in number when compared to photons and charged particles. Furthermore, neutrons allow for a backtracking of the emission point that is not affected by multiple scattering. Since neutrons can release a significant dose far away from the tumor region, a precise measurement of their flux, production energy and angle distributions is eagerly needed in order to improve the Treatment Planning Systems (TPS) software, so to predict not only the normal tissue toxicity in the target region but also the risk of late complications in the whole body. All the aforementioned issues underline the importance for an experimental effort devoted to the precise characterization of the neutron production gaining experimental access both to the emission point and production energy. The technical challenges posed by a neutron detector aiming for a high detection efficiency and good backtracking precision will be addressed within the MONDO (MOnitor for Neutron Dose in hadrOntherapy) project. The MONDO's main goal is to develop a tracking detector targeting fast and ultrafast secondary neutrons. The tracker is composed by a scintillating fiber matrix ð4 4 8 cm3Þ. The full reconstruction of protons, produced in elastic interactions, will be used to measure energy and direction of the impinging neutron. The neutron tracker will measure the neutron production yields, as a function of production angle and energy, using different therapeutic beams at CNAO in Pavia (protons, 12C ions and possibly 4He and 16O ions).
2015
Frontiers Detectors for Frontier Physics 13th Pisa Meeting on Advanced Detectors
GEM; Neutrons; Particle therapy; SPAD; Tracking detectors; Instrumentation; Nuclear and High Energy Physics
04 Pubblicazione in atti di convegno::04c Atto di convegno in rivista
MONDO: A neutron tracker for particle therapy secondary emission fluxes measurements / Marafini, M.; Patera, Vincenzo; Pinci, D.; Sarti, Alessio; Sciubba, Adalberto; Spiriti, E.. - In: NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH. SECTION A, ACCELERATORS, SPECTROMETERS, DETECTORS AND ASSOCIATED EQUIPMENT. - ISSN 0168-9002. - (2015). (Intervento presentato al convegno Frontiers Detectors for Frontier Physics 13th Pisa Meeting on Advanced Detectors tenutosi a Elba) [10.1016/j.nima.2015.10.109].
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/836286
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