Epithelial-to-mesenchymal transition (EMT) consists of a rapid and reversible change in the cellular phenotype toward the mesenchymal cell phenotype that facilitates cell migration and invasion of the tumor into surrounding tissues followed by metastasis. In the present study, we sought to determine the clinical significance of E-cadherin, N-cadherin, β-catenin, α-catenin, γ-catenin, caveolin-1, and vimentin in a cohort of patients with stage I to IVA laryngeal squamous cell carcinoma (LSCC) treated with surgery with or without adjuvant therapy using immunohistochemical analyses.
The prognostic role of E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma / Greco, Antonio; De Virgilio, Armando; Rizzo, Maria Ida; Pandolfi, Fabio; Rosati, Davide; De Vincentiis, Marco. - In: LARYNGOSCOPE. - ISSN 0023-852X. - 126:4(2016), pp. e148-e155. [10.1002/lary.25736]
Titolo: | The prognostic role of E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma | |
Autori: | GRECO, Antonio (Primo) ROSATI, DAVIDE (Penultimo) DE VINCENTIIS, Marco (Ultimo) | |
Data di pubblicazione: | 2016 | |
Rivista: | ||
Citazione: | The prognostic role of E-cadherin and β-catenin overexpression in laryngeal squamous cell carcinoma / Greco, Antonio; De Virgilio, Armando; Rizzo, Maria Ida; Pandolfi, Fabio; Rosati, Davide; De Vincentiis, Marco. - In: LARYNGOSCOPE. - ISSN 0023-852X. - 126:4(2016), pp. e148-e155. [10.1002/lary.25736] | |
Handle: | http://hdl.handle.net/11573/835318 | |
Appartiene alla tipologia: | 01a Articolo in rivista |
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