A stereoselective synthesis of threo-γ-hydroxy-β-l-lysine lactone is reported. The threo-amino alcohol functionality is introduced by iodine-mediated cyclocarbamation of the electron poor allylamine 6. The D-phenylalanine was used as starting material as synthetic equivalent to D-aspartic acid.
A concise and stereoselective synthesis of threo-gamma-hydroxy-L-beta-lysine lactone / Misiti, Domenico; G., Zappia; G., DELLE MONACHE. - In: LIEBIGS ANNALEN. - ISSN 0947-3440. - STAMPA. - (1996), pp. 235-238. [10.1002/jlac.199619960213]
A concise and stereoselective synthesis of threo-gamma-hydroxy-L-beta-lysine lactone
MISITI, Domenico;
1996
Abstract
A stereoselective synthesis of threo-γ-hydroxy-β-l-lysine lactone is reported. The threo-amino alcohol functionality is introduced by iodine-mediated cyclocarbamation of the electron poor allylamine 6. The D-phenylalanine was used as starting material as synthetic equivalent to D-aspartic acid.File allegati a questo prodotto
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