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A recent clinical report demonstrated that topical nerve growth factor (NGF) treatment in patients affected by corneal neurotrophic ulcers induced epithelial and stromal healing restoring corneal integrity. Mechanisms(s) undergoing these clinical NGF actions are still unclear. The aim of this study was to investigate the role of NGF in human and rat cornea physiopathology.

Nerve growth factor promotes corneal healing: structural, biochemical, and molecular analyses of rat and human corneas / Lambiase, Alessandro; Manni, L; Bonini, S; Rama, P; Micera, A; Aloe, L.. - In: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. - ISSN 0146-0404. - STAMPA. - 41:5(2000), pp. 1063-1069.

Nerve growth factor promotes corneal healing: structural, biochemical, and molecular analyses of rat and human corneas

LAMBIASE, ALESSANDRO;
2000

Abstract

A recent clinical report demonstrated that topical nerve growth factor (NGF) treatment in patients affected by corneal neurotrophic ulcers induced epithelial and stromal healing restoring corneal integrity. Mechanisms(s) undergoing these clinical NGF actions are still unclear. The aim of this study was to investigate the role of NGF in human and rat cornea physiopathology.
2000
Aged; Animals; Burns, Chemical; Cornea; Epithelium, Corneal; Eye Burns; Eye Injuries; Female; Humans; Immunoenzyme Techniques; In Situ Hybridization; Male; Middle Aged; Nerve Growth Factor; Organ Culture Techniques; RNA, Messenger; Rats; Rats, Sprague-Dawley; Receptor, trkA; Reverse Transcriptase Polymerase Chain Reaction; Wound Healing; Corneal Injuries
01 Pubblicazione su rivista::01a Articolo in rivista
Nerve growth factor promotes corneal healing: structural, biochemical, and molecular analyses of rat and human corneas / Lambiase, Alessandro; Manni, L; Bonini, S; Rama, P; Micera, A; Aloe, L.. - In: INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE. - ISSN 0146-0404. - STAMPA. - 41:5(2000), pp. 1063-1069.
01a Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/822305
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