To determinate the basal production of NGF and TGF-beta1 by amniotic membrane (AM) and to verify the presence of NGF receptors (trkA(NGFR) and p75(NTR)) in AM. Thereafter, to evaluate in an in vitro model if increasing concentrations of NGF are able to stimulate AM to produce and release TGF-beta1.
Nerve growth factor modulates in vitro the expression and release of TGF-beta1 by amniotic membrane / Coassin, Marco; Lambiase, Alessandro; Micera, Alessandra; Tirassa, Paola; Aloe, Luigi; Bonini, Stefano. - In: GRAEFE'S ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY. - ISSN 0721-832X. - STAMPA. - 244:4(2006), pp. 485-491. [10.1007/s00417-005-0098-0]
Nerve growth factor modulates in vitro the expression and release of TGF-beta1 by amniotic membrane
LAMBIASE, ALESSANDRO;
2006
Abstract
To determinate the basal production of NGF and TGF-beta1 by amniotic membrane (AM) and to verify the presence of NGF receptors (trkA(NGFR) and p75(NTR)) in AM. Thereafter, to evaluate in an in vitro model if increasing concentrations of NGF are able to stimulate AM to produce and release TGF-beta1.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
