Successful motor interactions require agents to anticipate what a partner is doing in order to predictively adjust their own movements. Although the neural underpinnings of the ability to predict others' action goals have been well explored during passive action observation, no study has yet clarified any critical neural substrate supporting interpersonal coordination during active, non-imitative (complementary) interactions. Here, we combine non-invasive inhibitory brain stimulation (continuous Theta Burst Stimulation) with a novel human-avatar interaction task to investigate a causal role for higher-order motor cortical regions in supporting the ability to predict and adapt to others' actions. We demonstrate that inhibition of left anterior intraparietal sulcus (aIPS), but not ventral premotor cortex, selectively impaired individuals' performance during complementary interactions. Thus, in addition to coding observed and executed action goals, aIPS is crucial in coding 'shared goals', that is, integrating predictions about one's and others' complementary actions.

Causative role of left aIPS in coding shared goals during human-avatar complementary joint actions / Sacheli, LUCIA MARIA; Candidi, Matteo; Era, Vanessa; Aglioti, Salvatore Maria. - In: NATURE COMMUNICATIONS. - ISSN 2041-1723. - STAMPA. - 6:(2015), pp. 1-11. [10.1038/ncomms8544]

Causative role of left aIPS in coding shared goals during human-avatar complementary joint actions

SACHELI, LUCIA MARIA
;
CANDIDI, MATTEO;ERA, VANESSA;AGLIOTI, Salvatore Maria
2015

Abstract

Successful motor interactions require agents to anticipate what a partner is doing in order to predictively adjust their own movements. Although the neural underpinnings of the ability to predict others' action goals have been well explored during passive action observation, no study has yet clarified any critical neural substrate supporting interpersonal coordination during active, non-imitative (complementary) interactions. Here, we combine non-invasive inhibitory brain stimulation (continuous Theta Burst Stimulation) with a novel human-avatar interaction task to investigate a causal role for higher-order motor cortical regions in supporting the ability to predict and adapt to others' actions. We demonstrate that inhibition of left anterior intraparietal sulcus (aIPS), but not ventral premotor cortex, selectively impaired individuals' performance during complementary interactions. Thus, in addition to coding observed and executed action goals, aIPS is crucial in coding 'shared goals', that is, integrating predictions about one's and others' complementary actions.
2015
observation; mirror neurons; mu rhythm
01 Pubblicazione su rivista::01a Articolo in rivista
Causative role of left aIPS in coding shared goals during human-avatar complementary joint actions / Sacheli, LUCIA MARIA; Candidi, Matteo; Era, Vanessa; Aglioti, Salvatore Maria. - In: NATURE COMMUNICATIONS. - ISSN 2041-1723. - STAMPA. - 6:(2015), pp. 1-11. [10.1038/ncomms8544]
File allegati a questo prodotto
File Dimensione Formato  
Sacheli_Causative_2015.pdf

accesso aperto

Note: Articolo pdf
Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Creative commons
Dimensione 850.85 kB
Formato Adobe PDF
850.85 kB Adobe PDF

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/798575
Citazioni
  • ???jsp.display-item.citation.pmc??? 15
  • Scopus 48
  • ???jsp.display-item.citation.isi??? 47
social impact