Previous studies have reported that protease inhibitors (PIs) can contribute to the glycaemic alterations however there are few trials about the direct effect of the single PI. The objective of the study was to evaluate the modifications of glucose and lipid profiles after the switch from lopinavir/ritonavir (LPV/r) to atazanavir, used as ritonavir-boosted (ATV/r) or un-boosted.
Impact of switching from lopinavir/ritonavir to boosted and un-boosted atazanavir on glucose metabolism: ATAzanavir & GLUcose metabolism (ATAGLU) sudy / D'Ettorre, Gabriella; Ceccarelli, Giancarlo; Zaccarelli, Mauro; ASCOLI BARTOLI, Tommaso; Bianchi, Luigi; Bellelli, Valeria; De Girolamo, Gabriella; Serafino, Sara; Giustini, Noemi; Mastroianni, Claudio Maria; Vullo, Vincenzo. - In: INTERNATIONAL JOURNAL OF STD & AIDS. - ISSN 0956-4624. - STAMPA. - (2016), pp. 1-6. [10.1177/0956462415590724]
Impact of switching from lopinavir/ritonavir to boosted and un-boosted atazanavir on glucose metabolism: ATAzanavir & GLUcose metabolism (ATAGLU) sudy
D'ETTORRE, Gabriella;CECCARELLI, GIANCARLO;ASCOLI BARTOLI, TOMMASO;BIANCHI, LUIGI;BELLELLI, VALERIA;De Girolamo, Gabriella;SERAFINO, SARA;GIUSTINI, NOEMI;MASTROIANNI, Claudio Maria;VULLO, Vincenzo
2016
Abstract
Previous studies have reported that protease inhibitors (PIs) can contribute to the glycaemic alterations however there are few trials about the direct effect of the single PI. The objective of the study was to evaluate the modifications of glucose and lipid profiles after the switch from lopinavir/ritonavir (LPV/r) to atazanavir, used as ritonavir-boosted (ATV/r) or un-boosted.| File | Dimensione | Formato | |
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