Basosquamous carcinoma (BSC) is a rare and aggressive type of basal cell carcinoma (BCC) more frequently involving head and neck region1 characterized by high tendency to recur locally or at distant sites. Metastasis have been observed with a latency period that can vary from 0 to 30 years.2 In some cases, first diagnosis of the skin lesion is consistent with BCC, and only after metastasis detection diagnosis of BSC has been done.3,4 Immunohistochemistry is useful to diagnose BSC: areas of squamous cell carcinoma are cytokeratin AE1, cytokeratin AE3, and cell adhesion molecule 52 positive and show variable staining with epithelial membrane antigen.

Basosquamous or basal cell carcinoma? The importance of the differential diagnosis / Terenzi, Valentina; Cassoni, Andrea; Della Monaca, Marco; Musio, Daniela; De Felice, Francesca; Tombolini, Vincenzo; Valentini, Valentino. - In: THE JOURNAL OF CRANIOFACIAL SURGERY. - ISSN 1049-2275. - STAMPA. - 26:6(2015), pp. 2026-2027. [10.1097/SCS.0000000000001910]

Basosquamous or basal cell carcinoma? The importance of the differential diagnosis

Terenzi, Valentina
Primo
;
Cassoni, Andrea
Secondo
;
Della Monaca, Marco;De Felice, Francesca;Tombolini, Vincenzo
Penultimo
;
Valentini, Valentino
Ultimo
2015

Abstract

Basosquamous carcinoma (BSC) is a rare and aggressive type of basal cell carcinoma (BCC) more frequently involving head and neck region1 characterized by high tendency to recur locally or at distant sites. Metastasis have been observed with a latency period that can vary from 0 to 30 years.2 In some cases, first diagnosis of the skin lesion is consistent with BCC, and only after metastasis detection diagnosis of BSC has been done.3,4 Immunohistochemistry is useful to diagnose BSC: areas of squamous cell carcinoma are cytokeratin AE1, cytokeratin AE3, and cell adhesion molecule 52 positive and show variable staining with epithelial membrane antigen.
2015
basosquamous carcinoma; basal cell carcinoma; differential diagnosis
01 Pubblicazione su rivista::01f Lettera, Nota
Basosquamous or basal cell carcinoma? The importance of the differential diagnosis / Terenzi, Valentina; Cassoni, Andrea; Della Monaca, Marco; Musio, Daniela; De Felice, Francesca; Tombolini, Vincenzo; Valentini, Valentino. - In: THE JOURNAL OF CRANIOFACIAL SURGERY. - ISSN 1049-2275. - STAMPA. - 26:6(2015), pp. 2026-2027. [10.1097/SCS.0000000000001910]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/787345
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