The aim of this review is to focus the current knowledge about mental and behavioral disorders in Usher syndrome. Previous studies described the presence of various mental disorders associated with Usher syndrome, suggesting possible mechanisms of association between these disorders. The most common manifestations are schizophrenia-like disorder and psychotic symptoms. Mood and behavioral disorders are rarely described, and often are associated with more complex cases in co-occurrence with other psychiatric disorders. Neuroimaging studies reported diffuse involvement of central nervous system (CNS) in Usher patients, suggesting a possible role of CNS damage in the pathogenesis of psychiatric manifestations. Genetic hypothesis and stress-related theories have also been proposed.

Psychosis, mood and behavioral disorders in usher syndrome: review of the literature / Domanico, Daniela; Fragiotta, Serena; Cutini, Alessandro; Grenga, Pier Luigi; Vingolo, Enzo Maria. - In: MEDICAL HYPOTHESIS DISCOVERY AND INNOVATION IN OPHTHALMOLOGY. - ISSN 2322-3219. - ELETTRONICO. - 4:2(2015), pp. 50-55.

Psychosis, mood and behavioral disorders in usher syndrome: review of the literature

DOMANICO, DANIELA
Primo
;
FRAGIOTTA, SERENA
Secondo
;
CUTINI, ALESSANDRO;VINGOLO, Enzo Maria
Ultimo
2015

Abstract

The aim of this review is to focus the current knowledge about mental and behavioral disorders in Usher syndrome. Previous studies described the presence of various mental disorders associated with Usher syndrome, suggesting possible mechanisms of association between these disorders. The most common manifestations are schizophrenia-like disorder and psychotic symptoms. Mood and behavioral disorders are rarely described, and often are associated with more complex cases in co-occurrence with other psychiatric disorders. Neuroimaging studies reported diffuse involvement of central nervous system (CNS) in Usher patients, suggesting a possible role of CNS damage in the pathogenesis of psychiatric manifestations. Genetic hypothesis and stress-related theories have also been proposed.
2015
hearing loss; psychosis; retinitis pigmentosa; schizophrenia; usher syndrome
01 Pubblicazione su rivista::01g Articolo di rassegna (Review)
Psychosis, mood and behavioral disorders in usher syndrome: review of the literature / Domanico, Daniela; Fragiotta, Serena; Cutini, Alessandro; Grenga, Pier Luigi; Vingolo, Enzo Maria. - In: MEDICAL HYPOTHESIS DISCOVERY AND INNOVATION IN OPHTHALMOLOGY. - ISSN 2322-3219. - ELETTRONICO. - 4:2(2015), pp. 50-55.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/786299
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