Very high energy electrons (VHEE) in the range from 100–250 MeV have the potential of becoming an alternative modality in radiotherapy because of their improved dosimetry properties compared with MV photons from contemporary medical linear accelerators. Due to the need for accurate dosimetry of small field size VHEE beams we have performed dose measurements using EBT2 Gafchromic® film. Calibration of the film has been carried out for beams of two different energy ranges: 20 MeV and 165 MeV from conventional radio frequency linear accelerators. In addition, EBT2 film has been used for dose measurements with 135 MeV electron beams produced by a laser-plasma wakefield accelerator. The dose response measurements and percentage depth dose profiles have been compared with calculations carried out using the general-purpose FLUKA Monte Carlo (MC) radiation transport code. The impact of induced radioactivity on film response for VHEEs has been evaluated using the MC simulations. A neutron yield
Dosimetry of very high energy electrons (VHEE) for radiotherapy applications: using radiochromic film measurements and Monte Carlo simulations / Subiel, A.; Moskvin, V.; Welsh, G. H.; Cipiccia, S.; Reboredo, D.; Evans, P.; Partridge, M.; Desrosiers, C.; Anania, M. P.; Cianchi, A.; Mostacci, Andrea; Chiadroni, E.; Di Giovenale, D.; Villa, F.; Pompili, R.; Ferrario, M.; Belleveglia, M.; Di Pirro, G.; Gatti, G.; Vaccarezza, C.; Seitz, B.; Isaac, R. C.; Brunetti, E.; Wiggins, S. M.; Ersfeld, B.; Islam, M. R.; Mendonca, M. S.; Sorensen, A.; Boyd, M.; Jaroszynski, D. A.. - In: PHYSICS IN MEDICINE AND BIOLOGY. - ISSN 0031-9155. - 59:(2014), pp. 5811-5829. [10.1088/0031-9155/59/19/5811]
Dosimetry of very high energy electrons (VHEE) for radiotherapy applications: using radiochromic film measurements and Monte Carlo simulations
MOSTACCI, Andrea;E. Chiadroni;
2014
Abstract
Very high energy electrons (VHEE) in the range from 100–250 MeV have the potential of becoming an alternative modality in radiotherapy because of their improved dosimetry properties compared with MV photons from contemporary medical linear accelerators. Due to the need for accurate dosimetry of small field size VHEE beams we have performed dose measurements using EBT2 Gafchromic® film. Calibration of the film has been carried out for beams of two different energy ranges: 20 MeV and 165 MeV from conventional radio frequency linear accelerators. In addition, EBT2 film has been used for dose measurements with 135 MeV electron beams produced by a laser-plasma wakefield accelerator. The dose response measurements and percentage depth dose profiles have been compared with calculations carried out using the general-purpose FLUKA Monte Carlo (MC) radiation transport code. The impact of induced radioactivity on film response for VHEEs has been evaluated using the MC simulations. A neutron yieldI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
