It has been recently demonstrated, in a pilot study [2], the feasibility of a smart controlled delivery from magnetic vesicles through an alternating magnetic field (AMF) with intensity significantly lower than the usual ones reported in literature unable to generate heat. Therefore, the drug release from the magnetically responsive vesicles (MLs) is controlled by mechanical oscillations induced alone on the magnetic nanoparticles by the AMF action. This could represent a clear advantage for therapeutic applications: the tissues are not affected neither by the temperature raise nor by theeddy currents induced by the field, thus preventing damage and safety secondary effects.

Exploring drug release from magnetic nanocarriers by low level magnetic stimulation / Spera, Romina; Apollonio, Francesca; Liberti, Micaela; Casadei, Maria Antonietta; C., Merla; R., Pinto; Petralito, Stefania. - STAMPA. - 1 st(2015), pp. 58-58. ((Intervento presentato al convegno European Conference on Pharmaceutics: Drug Delivery abstractbook tenutosi a Reims France.

Exploring drug release from magnetic nanocarriers by low level magnetic stimulation

SPERA, ROMINA;APOLLONIO, Francesca;LIBERTI, Micaela;CASADEI, Maria Antonietta;PETRALITO, Stefania
2015

Abstract

It has been recently demonstrated, in a pilot study [2], the feasibility of a smart controlled delivery from magnetic vesicles through an alternating magnetic field (AMF) with intensity significantly lower than the usual ones reported in literature unable to generate heat. Therefore, the drug release from the magnetically responsive vesicles (MLs) is controlled by mechanical oscillations induced alone on the magnetic nanoparticles by the AMF action. This could represent a clear advantage for therapeutic applications: the tissues are not affected neither by the temperature raise nor by theeddy currents induced by the field, thus preventing damage and safety secondary effects.
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/783588
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact