Exploring drug release from magnetic nanocarriers by low level magnetic stimulation

It has been recently demonstrated, in a pilot study [2], the feasibility of a smart controlled delivery from magnetic vesicles through an alternating magnetic field (AMF) with intensity significantly lower than the usual ones reported in literature unable to generate heat. Therefore, the drug release from the magnetically responsive vesicles (MLs) is controlled by mechanical oscillations induced alone on the magnetic nanoparticles by the AMF action. This could represent a clear advantage for therapeutic applications: the tissues are not affected neither by the temperature raise nor by theeddy currents induced by the field, thus preventing damage and safety secondary effects.