Endometriosis allergic or autoimmune disease: pathogenetic aspects - a case control study

The aim of this study was to evaluate between endometriosis and pathologies on an immune basis for the possible involvement of the immune system in the pathogenesis of endometriosis. In this retrospective study, data of 304 patiens with endometriosis and 318 without endometriosis were collected in a uniform manner for both groups and inserted into two databases, respectively, for patiens with and without endometriosis. The authors calculated the percentages of patients with allergies, autoimmune diseases, asthma in both groups, and later statistical analysis were performed with two different chisquare tets. The results obtained have shown that patients with endometriosis have a higher prevalence of allergies (p=0.0003) and coexistence of both allergies and autoimmune diseases (p=0.0274), compared to those without. The present study seems support the possible association between endometriosis and allergic disease. Endometriosis; Immune system diseases; Allergies; Autoimmune disease; Asthma.