The aim of this study is to evaluate the effect and performance of the new algorithm in cervical cancer screening program in two years’ experience of Latin (Italy). The female population was divided into two groups, the first group was referred to PAP test and the second one to hr-HPV test according to national guidelines. In two years the participation mean rate increased among women 35-64 compared to women aged 25-34. The primary PAP test positive rate and hr-HPV test positive rate were 4.0% and 5.2% respectively. The PAP test positive rate among hr-HPV+ women decreased from 2012 to 2013. Women hr-HPV+/PAP+ were referred immediately to colposcopy and this rate was 1.2%. The predictive positive value for CIN2+ to colposcopy was 10.9% in 2012 and 9.1% in 2013 while the detection rate for CIN2+ was 1.6% in 2012 and 1.4% in 2013. The stratification of the female population leds to a decreased inappropriate therapeutic path while the combination of hr-HPV test with PAP test in woman aged 35-64 lets obtain high levels specificity and sensitivity results.
The aim of this study is to evaluate the effect and performance of the new algorithm in cervical cancer screening program in two years’ experience of Latin (Italy). The female population was divided into two groups, the first group was referred to PAP test and the second one to hr-HPV test according to national guidelines. In two years the participation mean rate increased among women 35-64 compared to women aged 25-34. The primary PAP test positive rate and hr-HPV test positive rate were 4.0% and 5.2% respectively. The PAP test positive rate among hr-HPV+ women decreased from 2012 to 2013. Women hr-HPV+/PAP+ were referred immediately to colposcopy and this rate was 1.2%. The predictive positive value for CIN2+ to colposcopy was 10.9% in 2012 and 9.1% in 2013 while the detection rate for CIN2+ was 1.6% in 2012 and 1.4% in 2013. The stratification of the female population leds to a decreased inappropriate therapeutic path while the combination of hr-HPV test with PAP test in woman aged 35-64 lets obtain high levels specificity and sensitivity results.
Primary HPV test screening in cervical cancer: a two-year experience of a single screening center in Latina (Italy) / Chiappetta, Caterina; Lendaro, Eugenio; J., Cacciotti; R., Zaralli; C., Puggioni; G., Migliore; P., Bellardini; N., Porta; Petrozza, Vincenzo; DELLA ROCCA, Carlo; DI CRISTOFANO, Claudio. - In: EUROPEAN JOURNAL OF GYNAECOLOGICAL ONCOLOGY. - ISSN 0392-2936. - STAMPA. - 5:XXXVI(2015), pp. 569-573. [10.12892/ejgo2737.2015]
Primary HPV test screening in cervical cancer: a two-year experience of a single screening center in Latina (Italy).
CHIAPPETTA, CATERINA;LENDARO, Eugenio;PETROZZA, Vincenzo;DELLA ROCCA, Carlo;DI CRISTOFANO, CLAUDIO
2015
Abstract
The aim of this study is to evaluate the effect and performance of the new algorithm in cervical cancer screening program in two years’ experience of Latin (Italy). The female population was divided into two groups, the first group was referred to PAP test and the second one to hr-HPV test according to national guidelines. In two years the participation mean rate increased among women 35-64 compared to women aged 25-34. The primary PAP test positive rate and hr-HPV test positive rate were 4.0% and 5.2% respectively. The PAP test positive rate among hr-HPV+ women decreased from 2012 to 2013. Women hr-HPV+/PAP+ were referred immediately to colposcopy and this rate was 1.2%. The predictive positive value for CIN2+ to colposcopy was 10.9% in 2012 and 9.1% in 2013 while the detection rate for CIN2+ was 1.6% in 2012 and 1.4% in 2013. The stratification of the female population leds to a decreased inappropriate therapeutic path while the combination of hr-HPV test with PAP test in woman aged 35-64 lets obtain high levels specificity and sensitivity results.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
