N-acetyl-L-cysteine exerts a complex action on endometrial cells, involving regulation of gene expression and protein activity and location, all converging into a decreased proliferation and a switch toward a differentiating, less invasive, and less inflammatory phenotype. Also considering the lack of undesired side effects, including unaffected fertility potential, this suggests a beneficial use of NAC in endometriosis clinical treatment. Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.
More than antioxidant: N-acetyl-L-cysteine in a murine model of endometriosis / Eugenia, Pittaluga; Graziella, Costa; Ewa, Krasnowska; Brunelli, Roberto; Thomas, Lundeberg; Porpora, Maria Grazia; Daniela, Santucci; Tiziana, Parasassi. - In: FERTILITY AND STERILITY. - ISSN 0015-0282. - STAMPA. - 94:7(2010), pp. 2905-2908. [10.1016/j.fertnstert.2010.06.038]
More than antioxidant: N-acetyl-L-cysteine in a murine model of endometriosis
BRUNELLI, Roberto;PORPORA, Maria Grazia;
2010
Abstract
N-acetyl-L-cysteine exerts a complex action on endometrial cells, involving regulation of gene expression and protein activity and location, all converging into a decreased proliferation and a switch toward a differentiating, less invasive, and less inflammatory phenotype. Also considering the lack of undesired side effects, including unaffected fertility potential, this suggests a beneficial use of NAC in endometriosis clinical treatment. Copyright © 2010 American Society for Reproductive Medicine. Published by Elsevier Inc. All rights reserved.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
