Calix[4]arenes derivatives 1 and 2, featuring two guanidine units at the upper rim, catalyze the transesteri fi cation of diribonucleoside monophosphates much more e ff ectively than that of HPNP. Rate accelerations relative to the background range from 10^3 to 10^4-fold, and approach 10^5-fold with the most favorable substrate-catalyst combinations.
Diguanidinocalix[4]arenes as effective and selective catalysts of the cleavage of diribonucleoside monophosphates / Salvio, Riccardo; Roberta, Cacciapaglia; Mandolini, Luigi; Francesco, Sansone; Alessandro, Casnati. - In: RSC ADVANCES. - ISSN 2046-2069. - STAMPA. - 4:(2014), pp. 34412-34416. [10.1039/C4RA05751A]
Diguanidinocalix[4]arenes as effective and selective catalysts of the cleavage of diribonucleoside monophosphates
SALVIO, RICCARDO;MANDOLINI, Luigi;
2014
Abstract
Calix[4]arenes derivatives 1 and 2, featuring two guanidine units at the upper rim, catalyze the transesteri fi cation of diribonucleoside monophosphates much more e ff ectively than that of HPNP. Rate accelerations relative to the background range from 10^3 to 10^4-fold, and approach 10^5-fold with the most favorable substrate-catalyst combinations.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
