Methadone substitution therapy for drug The substitution of methadone for heroin abusers has arisen recently and has resulted in various problems of both medico-legal and juridical importancemedico-legal problems r. elated to These kind of problems the interpretation of methadone users deaths. These problemsare b concern the difficult definition of the actual causative role of the patient’s pre-existing pathologies and/or conditions and pharmacological interactions. In particular, in our report we decided to stress what the international literature already evidenced, that is the need of a systematic anatomical- pathology examination to integrate the informations given by the chemical-toxicological samples and circumstantial evidence. oth of medical and juridical importance cause they usually concern methadone associated deaths or the prescription of methadone resulting in criminal prosecutions concerning physicians. We present the case in which a 40 year old adult female drug addict, died. Toxicological exams showed an acute intoxication of methadone in correlation with an extensive bilateral bronchopneumonia. This analysis is done using background informations concerning the management of alternative therapies and the available literature.
La terapia sostitutiva con metadone nei soggetti tossicodipendenti ha comportato problematiche sia di rilevanza medico-legale sia di tipo giuridico correlate con le difficoltà di inquadramento delle cause di morte nei soggetti assuntori di metadone. Tali difficoltà risiedono nella necessità di definire l’effettivo ruolo causale svolto da patologie e/o condizioni preesistenti del paziente e l’interazione con altre sostanze farmacologiche. In particolare nel loro lavoro gli Autori segnalano confermando quanto già di fatto riportato nella letteratura internazionale sul tema, la necessità di effettuare uno studio anatomopatologico sistematico che integri le indicazioni fornite dall’indagine chimico-tossicologica e i dati anamnestico-circostanziali.
Decessi metadone-correlati: esiste una causalità esclusiva? / Aromatario, Mariarosaria; D., Lucidi; Zoppis, Silvia; Bottoni, Edoardo; Sestili, Cristina; Ciallella, Costantino. - In: ZACCHIA. - ISSN 0044-1570. - STAMPA. - Supplemento:85(2012), pp. 381-392.
Decessi metadone-correlati: esiste una causalità esclusiva?
AROMATARIO, MARIAROSARIA;ZOPPIS, SILVIA;BOTTONI, EDOARDO;SESTILI, CRISTINA;CIALLELLA, Costantino
2012
Abstract
Methadone substitution therapy for drug The substitution of methadone for heroin abusers has arisen recently and has resulted in various problems of both medico-legal and juridical importancemedico-legal problems r. elated to These kind of problems the interpretation of methadone users deaths. These problemsare b concern the difficult definition of the actual causative role of the patient’s pre-existing pathologies and/or conditions and pharmacological interactions. In particular, in our report we decided to stress what the international literature already evidenced, that is the need of a systematic anatomical- pathology examination to integrate the informations given by the chemical-toxicological samples and circumstantial evidence. oth of medical and juridical importance cause they usually concern methadone associated deaths or the prescription of methadone resulting in criminal prosecutions concerning physicians. We present the case in which a 40 year old adult female drug addict, died. Toxicological exams showed an acute intoxication of methadone in correlation with an extensive bilateral bronchopneumonia. This analysis is done using background informations concerning the management of alternative therapies and the available literature.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
