9 subjects with myasthenia gravis, chronically treated with prednisone, underwent an open clinical trial with cyclosporine, an immunosuppressive and immunomodulator drug. Preliminary results after one year of treatment show that cyclosporine induces a further improvement of myasthenic symptoms, and that prednisone may be reduced or discontinued without relapse of clinical symptoms. Side effects of cyclosporine are very frequent and largely influence the treatment
Results of an open trial of cyclosporine in a group of steroido-dependent myasthenic subjects / Antonini, Giovanni; Bove, R; Filippini, Cesare; Millefiorini, Marcello. - In: CLINICAL NEUROLOGY AND NEUROSURGERY. - ISSN 0303-8467. - 92:(1990), pp. 317-321. [10.1016/0303-8467(90)90057-C]
Results of an open trial of cyclosporine in a group of steroido-dependent myasthenic subjects
ANTONINI, Giovanni;FILIPPINI, Cesare;MILLEFIORINI, Marcello
1990
Abstract
9 subjects with myasthenia gravis, chronically treated with prednisone, underwent an open clinical trial with cyclosporine, an immunosuppressive and immunomodulator drug. Preliminary results after one year of treatment show that cyclosporine induces a further improvement of myasthenic symptoms, and that prednisone may be reduced or discontinued without relapse of clinical symptoms. Side effects of cyclosporine are very frequent and largely influence the treatmentI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
