Besides the chemotaxonomic value, nowadays determination of biodiversity and chemical variability has a commercial impact. The exact identity of raw material and constituents of botanical products, such as food supplements or herbal remedies, is a very important argument, being the real prerequisite for quality control and traceability, followed by the determination of active components. However, the analytical approach must consider the natural great variability in secondary metabolites and product form, such as in extracts. Against the reductive approach, on the basis of single chemical standards, so far dominant in Pharmacopoeias monographs, we report applications and utility of the high-performance thin-layer chromatography fingerprint in determination of species of the same genus, of populations of the same species and of different drugs of the same plant.

HPTLC determination of chemical composition variability in raw material used in botanicals / Toniolo, Chiara; Nicoletti, Marcello; Maggi, Filippo; Venditti, Alessandro. - In: NATURAL PRODUCT RESEARCH. - ISSN 1478-6427. - 28:2(2014), pp. 119-126. [10.1080/14786419.2013.852546]

HPTLC determination of chemical composition variability in raw material used in botanicals

Toniolo, Chiara;Nicoletti, Marcello;Venditti, Alessandro
2014

Abstract

Besides the chemotaxonomic value, nowadays determination of biodiversity and chemical variability has a commercial impact. The exact identity of raw material and constituents of botanical products, such as food supplements or herbal remedies, is a very important argument, being the real prerequisite for quality control and traceability, followed by the determination of active components. However, the analytical approach must consider the natural great variability in secondary metabolites and product form, such as in extracts. Against the reductive approach, on the basis of single chemical standards, so far dominant in Pharmacopoeias monographs, we report applications and utility of the high-performance thin-layer chromatography fingerprint in determination of species of the same genus, of populations of the same species and of different drugs of the same plant.
File allegati a questo prodotto
File Dimensione Formato  
Toniolo_HPTLC_2014.pdf

solo gestori archivio

Tipologia: Versione editoriale (versione pubblicata con il layout dell'editore)
Licenza: Tutti i diritti riservati (All rights reserved)
Dimensione 474.68 kB
Formato Adobe PDF
474.68 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11573/742399
Citazioni
  • ???jsp.display-item.citation.pmc??? 7
  • Scopus 38
  • ???jsp.display-item.citation.isi??? 36
social impact