A temperature-sensitive lethal mutant of Drosophila melanogaster was used to identify an essential cell cycle function that is necessary for the mitotic condensation of heterochromatic but not of euchromatic portions of the genome. This mutant is an allele at a locus (mus-101) identified earlier by the use of mutagen-sensitive mutants. The data suggest that the mutagen-sensitive and repair-defective phenotypes of viable mus-101 mutants result from a disruption in chromosome organization.

A gene controlling condensation of heterochromatin in Drosophila melanogaster / Gatti, Maurizio; Smith, D. A.; Baker, B. S.. - In: SCIENCE. - ISSN 0036-8075. - STAMPA. - 221:(1983), pp. 83-85.

A gene controlling condensation of heterochromatin in Drosophila melanogaster

GATTI, MAURIZIO;
1983

Abstract

A temperature-sensitive lethal mutant of Drosophila melanogaster was used to identify an essential cell cycle function that is necessary for the mitotic condensation of heterochromatic but not of euchromatic portions of the genome. This mutant is an allele at a locus (mus-101) identified earlier by the use of mutagen-sensitive mutants. The data suggest that the mutagen-sensitive and repair-defective phenotypes of viable mus-101 mutants result from a disruption in chromosome organization.
1983
01 Pubblicazione su rivista::01a Articolo in rivista
A gene controlling condensation of heterochromatin in Drosophila melanogaster / Gatti, Maurizio; Smith, D. A.; Baker, B. S.. - In: SCIENCE. - ISSN 0036-8075. - STAMPA. - 221:(1983), pp. 83-85.
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/6868
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