Early menopause and related vaginal atrophy is a well known side-effect of hormone adjuvant treatment in breast cancer patients, particularly during aromatase-inhibitors therapy. Due to estrogens contra-indication, proper therapy for such symptom remains often an inadequately addressed clinical problem. After an accurate assessment of the risk/benefit ratio, vaginal low-dose estrogen treatment (better with estriol) may have a role in controlling vaginal atrophy in selected and informed breast cancer women.

Vaginal atrophy in breast cancer survivors: role of vaginal estrogen therapy / Luciano, Mariani; Angiolo, Gadducci; Enrico, Vizza; Tomao, Silverio; Patrizia, Vici. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - STAMPA. - 29:1(2013), pp. 25-29. [10.3109/09513590.2012.705389]

Vaginal atrophy in breast cancer survivors: role of vaginal estrogen therapy

TOMAO, SILVERIO;
2013

Abstract

Early menopause and related vaginal atrophy is a well known side-effect of hormone adjuvant treatment in breast cancer patients, particularly during aromatase-inhibitors therapy. Due to estrogens contra-indication, proper therapy for such symptom remains often an inadequately addressed clinical problem. After an accurate assessment of the risk/benefit ratio, vaginal low-dose estrogen treatment (better with estriol) may have a role in controlling vaginal atrophy in selected and informed breast cancer women.
2013
drug therapy/epidemiology; estriol; vaginal estrogen therapy; atrophy; neoplasm recurrence; aromatase inhibitors; vagina; tamoxifen and aromatase inhibitors therapy; drug effects/pathology; menopause treatment-related; breast cancer survivors; chemically induced/drug therapy/pathology; intravaginal; tamoxifen; administration /&/ dosage; administration /&/ dosage/adverse effects; antineoplastic agents; epidemiology; humans; breast neoplasms; female; hormonal; local; survivors; administration; risk factors; vaginal diseases; estrogens
01 Pubblicazione su rivista::01a Articolo in rivista
Vaginal atrophy in breast cancer survivors: role of vaginal estrogen therapy / Luciano, Mariani; Angiolo, Gadducci; Enrico, Vizza; Tomao, Silverio; Patrizia, Vici. - In: GYNECOLOGICAL ENDOCRINOLOGY. - ISSN 0951-3590. - STAMPA. - 29:1(2013), pp. 25-29. [10.3109/09513590.2012.705389]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/675862
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