Consecutive non-replicate clinical isolates (n=191) of carbapenem non-susceptible Enterobacteriaceae were collected from 21 hospital laboratories across Italy from November 2013 to April 2014 as part of the European Survey on Carbapenemase-producing Enterobacteriaceae (EuSCAPE) project. Klebsiella pneumonia carbapenemase-producing K. pneumoniae (KPC-KP) represented 178 (93%) isolates with 76 (43%) respectively resistant to colistin, a key drug for treating carbapenamase-producing Enterobacteriaceae. KPC-KP colistin-resistant isolates were detected in all participating laboratories. This underscores a concerning evolution of colistin resistance in a setting of high KPC-KP endemicity.
Colistin resistance superimposed to endemic carbapenem-resistant Klebsiella pneumoniae: a rapidly evolving problem in Italy, November 2013 to April 2014 / Monaco, M; Giani, T; Raffone, M; Arena, F; Garcia Fernandez, A; Pollini, S; Network EuSCAPE, Italy; Grundmann, H; Pantosti, A; Rossolini, Gm; Collaborators, ; Barbaro, A; Campion, L; Catania, M; De Bernochi, A; Di Taranto, Am; Dusi, P; Grandesso, S; Luzzaro, F; Manso, E; Meledandri, M; Mencacci, A; Milano, F; Parisi, G; Pecile, P; Restelli, A; Rocchetti, A; Arrigo, C; Rossi, M; Santino, Iolanda; Sarti, M; Sartor, A.. - In: EUROSURVEILLANCE. - ISSN 1025-496X. - ELETTRONICO. - 19(42):(2014).
Colistin resistance superimposed to endemic carbapenem-resistant Klebsiella pneumoniae: a rapidly evolving problem in Italy, November 2013 to April 2014.
SANTINO, Iolanda;
2014
Abstract
Consecutive non-replicate clinical isolates (n=191) of carbapenem non-susceptible Enterobacteriaceae were collected from 21 hospital laboratories across Italy from November 2013 to April 2014 as part of the European Survey on Carbapenemase-producing Enterobacteriaceae (EuSCAPE) project. Klebsiella pneumonia carbapenemase-producing K. pneumoniae (KPC-KP) represented 178 (93%) isolates with 76 (43%) respectively resistant to colistin, a key drug for treating carbapenamase-producing Enterobacteriaceae. KPC-KP colistin-resistant isolates were detected in all participating laboratories. This underscores a concerning evolution of colistin resistance in a setting of high KPC-KP endemicity.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
