Cadmium (Cd) is a metal, which induces hypertension in animals. This may not be relevant to the human population because the number of studies is inconsistent. Our aim is to identify an association between levels of blood/urinary cadmium and blood pressure in a group of employees of the municipal police assigned to outdoor activities. 349 subjects of both sexes were enrolled and sorted on the basis of gender, job function and smoking habit. Blood and urinary cadmium levels and blood pressure readings were collected for each subject. The data were subjected to statistical evaluation. Pearson correlation coefficient between the variables and a linear regression curve was drawn. After eliminating the confounding factors, the multiple linear regression analysis assessed statistical differences. Associations were considered significant at p < 0.05. The Pearson correlation showed a positive association between urinary cadmium levels and blood pressure especially for groups of women and non-smokers. The simple and multiple linear regression and t-tests confirmed these associations and underlined the influence cadmium has on diastolic blood pressure, higher than systolic blood pressure. No association was found between blood cadmium and blood pressure. In conclusion, we can say that there is a statistically significant association between urinary cadmium and diastolic blood pressure, supporting the hypothesis that cadmium has a long-term effect on diastolic blood pressure (BP).

Cadmium blood/urine levels and blood pressure in workers occupationally exposed to urban stressor / Caciari, T; Sancini, Angela; Tomei, Francesco; Antetomaso, Luigi; Tomei, Gianfranco; Scala, Barbara; Sinibaldi, Federica; DI PASTENA, Claudia; Andreozzi, Giorgia; Nardone, Nadia; Schifano, MARIA PIA; Corbosiero, Paola; Capozzella, Assuntina; DE SIO, Simone; Ciarrocca, Manuela. - In: ANNALI DI IGIENE MEDICINA PREVENTIVA E DI COMUNITÀ. - ISSN 1120-9135. - STAMPA. - 24:5(2012), pp. 417-428.

Cadmium blood/urine levels and blood pressure in workers occupationally exposed to urban stressor

SANCINI, angela;TOMEI, Francesco;ANTETOMASO, LUIGI;TOMEI, GIANFRANCO;SCALA, BARBARA;SINIBALDI, FEDERICA;DI PASTENA, CLAUDIA;ANDREOZZI, giorgia;NARDONE, NADIA;SCHIFANO, MARIA PIA;CORBOSIERO, PAOLA;CAPOZZELLA, ASSUNTINA;DE SIO, SIMONE;CIARROCCA, Manuela
2012

Abstract

Cadmium (Cd) is a metal, which induces hypertension in animals. This may not be relevant to the human population because the number of studies is inconsistent. Our aim is to identify an association between levels of blood/urinary cadmium and blood pressure in a group of employees of the municipal police assigned to outdoor activities. 349 subjects of both sexes were enrolled and sorted on the basis of gender, job function and smoking habit. Blood and urinary cadmium levels and blood pressure readings were collected for each subject. The data were subjected to statistical evaluation. Pearson correlation coefficient between the variables and a linear regression curve was drawn. After eliminating the confounding factors, the multiple linear regression analysis assessed statistical differences. Associations were considered significant at p < 0.05. The Pearson correlation showed a positive association between urinary cadmium levels and blood pressure especially for groups of women and non-smokers. The simple and multiple linear regression and t-tests confirmed these associations and underlined the influence cadmium has on diastolic blood pressure, higher than systolic blood pressure. No association was found between blood cadmium and blood pressure. In conclusion, we can say that there is a statistically significant association between urinary cadmium and diastolic blood pressure, supporting the hypothesis that cadmium has a long-term effect on diastolic blood pressure (BP).
01 Pubblicazione su rivista::01a Articolo in rivista
Cadmium blood/urine levels and blood pressure in workers occupationally exposed to urban stressor / Caciari, T; Sancini, Angela; Tomei, Francesco; Antetomaso, Luigi; Tomei, Gianfranco; Scala, Barbara; Sinibaldi, Federica; DI PASTENA, Claudia; Andreozzi, Giorgia; Nardone, Nadia; Schifano, MARIA PIA; Corbosiero, Paola; Capozzella, Assuntina; DE SIO, Simone; Ciarrocca, Manuela. - In: ANNALI DI IGIENE MEDICINA PREVENTIVA E DI COMUNITÀ. - ISSN 1120-9135. - STAMPA. - 24:5(2012), pp. 417-428.
File allegati a questo prodotto
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/659635
 Attenzione

Attenzione! I dati visualizzati non sono stati sottoposti a validazione da parte dell'ateneo

Citazioni
  • ???jsp.display-item.citation.pmc??? 2
  • Scopus 15
  • ???jsp.display-item.citation.isi??? ND
social impact