Xanthogranulomatous inflammation (XGI) is a disease of unknown origin, most frequently described in the kidney and gallbladder; its localization in the colorectal tract is extremely rare. The extension of the typical inflammatory process to the surrounding tissues may lead to misdiagnosis as cancer. We report the case of a 56-year-old woman presenting to the Emergency Department with pain, increased levels of α1 and α2 proteins and C-reactive protein (17.5 mg/dL; normal value 0-0.5), and a palpable mass, localized in the right lower quadrant of the abdomen. A computed tomography scan showed a large right cecal mass with necrotic areas, local inflammation of retroperitoneal fat, and enlargement of local lymph nodes. Because of the high suspicion of colic abscess as well as malignancy and worsening of the clinical condition, the patient underwent right colectomy after 4 d of antibiotic treatment. Pathology revealed xanthogranulomatous inflammation involving the ileocecal valve. We review the reports of large bowel tract XGI in the international literature.

Acute abdomen: Rare and unusual presentation of right colic xanthogranulomatosis / Addario Chieco, P; Giaccaglia, Valentina; Uccini, Stefania; Ziparo, Vincenzo; Antolino, Laura; Centanini, Francesca; Cunsolo, GAETANO VINCENZO; Sparagna, Alessandra. - In: WORLD JOURNAL OF GASTROENTEROLOGY. - ISSN 1007-9327. - STAMPA. - 20:26(2014), pp. 8717-8721. [10.3748/wjg.v20.i26.8717]

Acute abdomen: Rare and unusual presentation of right colic xanthogranulomatosis

GIACCAGLIA, VALENTINA;UCCINI, Stefania;ZIPARO, Vincenzo;ANTOLINO, LAURA;CENTANINI, FRANCESCA;CUNSOLO, GAETANO VINCENZO;
2014

Abstract

Xanthogranulomatous inflammation (XGI) is a disease of unknown origin, most frequently described in the kidney and gallbladder; its localization in the colorectal tract is extremely rare. The extension of the typical inflammatory process to the surrounding tissues may lead to misdiagnosis as cancer. We report the case of a 56-year-old woman presenting to the Emergency Department with pain, increased levels of α1 and α2 proteins and C-reactive protein (17.5 mg/dL; normal value 0-0.5), and a palpable mass, localized in the right lower quadrant of the abdomen. A computed tomography scan showed a large right cecal mass with necrotic areas, local inflammation of retroperitoneal fat, and enlargement of local lymph nodes. Because of the high suspicion of colic abscess as well as malignancy and worsening of the clinical condition, the patient underwent right colectomy after 4 d of antibiotic treatment. Pathology revealed xanthogranulomatous inflammation involving the ileocecal valve. We review the reports of large bowel tract XGI in the international literature.
Abdominal abscess; Abdominal mass; Large bowel xanthogranulomatosis; Xanthogranulomatosis; Abdomen, Acute; Biopsy; Colectomy; Colic; Colonic Neoplasms; Diagnosis, Differential; Female; Granuloma; Humans; Ileal Diseases; Ileocecal Valve; Middle Aged; Predictive Value of Tests; Tomography, X-Ray Computed; Xanthomatosis; Gastroenterology; Medicine (all)
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Acute abdomen: Rare and unusual presentation of right colic xanthogranulomatosis / Addario Chieco, P; Giaccaglia, Valentina; Uccini, Stefania; Ziparo, Vincenzo; Antolino, Laura; Centanini, Francesca; Cunsolo, GAETANO VINCENZO; Sparagna, Alessandra. - In: WORLD JOURNAL OF GASTROENTEROLOGY. - ISSN 1007-9327. - STAMPA. - 20:26(2014), pp. 8717-8721. [10.3748/wjg.v20.i26.8717]
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11573/652411
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