Aims: To evaluate technical issues and clinical outcomes after postoperative volumetric-modulated arc therapy (VMAT) in two cases of malignant lacrimal gland cancer. Patients & methods: Patients were treated by postoperative VMAT and post-treatment clinical outcomes were followed-up to 18 months. Results: Dosimetric results were acceptable and acute toxicity was manageable in both patients. No evidence of disease was found at latest follow-up. One patient underwent corneal transplant for central corneal ulceration, experiencing reduction of visual acuity. Conclusion: Postoperative VMAT for treatment of lacrimal gland tumors offers improved outcome, with manageable side effects. In the context of photon beam radiotherapy, VMAT emerged as a valuable treatment option for these malignant tumors.
Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma: two case reports and literature review / Orlandi, E., Takanen, S., Giandini, T., Iannacone, E., Fontanella, W., Locati, L., Carrara, M., Bossi, P., Bergamini, C., Granata, R., Tombolini, V., Ibba, T., Licitra, L., Pignoli, E., Fallai, C.. - In: FUTURE ONCOLOGY. - ISSN 1479-6694. - ELETTRONICO. - 10:14(2014), pp. 2111-2120. [10.2217/fon.14.148]
Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma: two case reports and literature review.
TAKANEN, SILVIA;TOMBOLINI, Vincenzo;
2014
Abstract
Aims: To evaluate technical issues and clinical outcomes after postoperative volumetric-modulated arc therapy (VMAT) in two cases of malignant lacrimal gland cancer. Patients & methods: Patients were treated by postoperative VMAT and post-treatment clinical outcomes were followed-up to 18 months. Results: Dosimetric results were acceptable and acute toxicity was manageable in both patients. No evidence of disease was found at latest follow-up. One patient underwent corneal transplant for central corneal ulceration, experiencing reduction of visual acuity. Conclusion: Postoperative VMAT for treatment of lacrimal gland tumors offers improved outcome, with manageable side effects. In the context of photon beam radiotherapy, VMAT emerged as a valuable treatment option for these malignant tumors.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
