In this paper we find a new asymptotic expansion valid in enzymatic reactions where the total amount of enzyme exceeds greatly the total amount of substrate. In such case it is well known that the Michelis-Menten approximation is no longer valid; therefore our asymptotic expansion is a new tool to approximate in a closed form the concentrations of the reactants in presence of an enzyme excess. © 2010 American Institute of Physics.
Asymptotic expansion in enzyme reactions with high enzyme concentrations / Bersani, Alberto Maria; Dell'Acqua, Guido. - STAMPA. - 1281:(2010), pp. 720-723. (Intervento presentato al convegno International Conference on Numerical Analysis and Applied Mathematics 2010, ICNAAM-2010 tenutosi a Rhodes nel 19 September 2010 through 25 September 2010) [10.1063/1.3498581].
Asymptotic expansion in enzyme reactions with high enzyme concentrations
BERSANI, Alberto Maria;DELL'ACQUA, Guido
2010
Abstract
In this paper we find a new asymptotic expansion valid in enzymatic reactions where the total amount of enzyme exceeds greatly the total amount of substrate. In such case it is well known that the Michelis-Menten approximation is no longer valid; therefore our asymptotic expansion is a new tool to approximate in a closed form the concentrations of the reactants in presence of an enzyme excess. © 2010 American Institute of Physics.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
